IP Library › Granted Patent US 7,052,860
Granted Patent B2
US 7,052,860 · App. 09/995,493 · Granted May 30, 2006

Identification of

Assignee: University of Florida Research Foundation
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Quick Facts
Patent No.
US 7,052,860
App. No.
09/995,493
Granted
May 30, 2006
Kind
B2
Abstract

Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans.

Claims (9)

1. A method of detecting the presence or absence of A. actinomycetemcomitans or an A. actinomycetemcomitans antigen in a test sample comprising:

contacting a test sample with an antibody or a fragment thereof that specifically binds to a purified immunogenic polypeptide consisting of SEQ ID NO:52, wherein the antibody or fragment thereof specifically binds A. actinomycetemcomitans or an A. actinomycetemcomitans antigen under conditions that allow formation of an immunocomplex between the antibody and the A. actinomycetemcomitans or the A. actinomycetemcomitans antigen; and

detecting an immunocomplex,

wherein detection of the immunocomplex indicates the presence of A. actinomycetemcomitans or an A. actinomycetemcomitans antigen in the test sample.

2. The method of claim 1 , wherein the A. actinomycetemcomitans antigen is expressed in vivo during infection of an animal.

3. A method of detecting presence or absence of an A. actinomycetemcomitans antibody in a test sample comprising:

contacting a test sample with a purified immunogenic polypeptide consisting of SEQ ID NO:52, wherein the polypeptide specifically binds an A. actinomycetemcomitans antibody under conditions that allow formation of an immunocomplex between the antibody and the polypeptide; and

detecting an immunocomplex,

wherein detection of the immunocomplex indicates the presence of A. actinomycetemcomitas antibody in the test sample.

Assignments (4)
CONFIRMATORY LICENSE Recorded Jul 26, 2016
From: UNIVERSITY OF FLORIDA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039462/0091 →
CONFIRMATORY LICENSE Recorded Aug 13, 2008
From: UNIVERSITY OF FLORIDA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021377/0247 →
CORRECTIVE COVERSHEET TO CORRECT ERRONEOUS SERIAL NUMBER RECORDED AT REEL/014069/0641 ON MAY 16, 2003. Recorded Nov 12, 2003
From: FLORIDA, UNIVERSITY OF
To: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION
Reel/Frame 014682/0076 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2002
From: HANDFIELD, MARTIN; HILLMAN, JEFFREY DANIEL; PROGULSKE-FOX, ANN
To: FLORIDA, UNIVERSITY OF
Reel/Frame 012669/0228 →
Continuity (1)
Related Publication 20060035293A1 · Feb 16, 2006