4-(oxazolopyridin-2-yl)-1,4-diazabicyclo-[3.2.2]nonane derivatives, preparation and therapeutic use thereof
View Patent ↗Compound corresponding to the general formula (I) in which R 2 represents a chlorine atom, a methyl group or a 3-thienyl group. Therapeutic application.
1. A compound corresponding to the general formula (I)
in which R 2 represents a 3-thienyl group, in the form of a base or of an acid-addition salt.
2. 4-(6-Thien-3-yl-oxazolo[4,5-b]pyrid-2-yl)-1,4-diazabicyclo[3.2.2]nonane in the form of a base or an acid-addition salt according to claim 1 .
3. 4-(6-Thien-3-yl-oxazolo[4,5-b]pyrid-2-yl)-1,4-diazabicyclo[3.2.2]nonane hydrobromide 1:2 according to claim 2 .
4. A pharmaceutical composition containing a compound as claimed in claim 1 and an excipient.
5. A pharmaceutical composition containing a compound as claimed in claim 2 and an excipient.
6. A pharmaceutical composition containing a compound as claimed in claim 3 and an excipient.
7. A method for the treatment of a disease selected from the group consisting of schizophrenia, Alzheimer's disease, Parkinson's disease, Down's syndrome, Korsakoff's alcoholic syndrome, vascular dementia, depression, anxiety, panic attack and obsessive-compulsive behavior, which comprises administering to a patient in need of such treatment an effective amount of a compound as claimed in claim 1 .
8. A method for the treatment of a disease selected from the group consisting of schizophrenia, Alzheimer's disease, Parkinson's disease, Down's syndrome, Korsakoff's alcoholic syndrome, vascular dementia, depression, anxiety, panic attack and obsessive-compulsive behavior, which comprises administering to a patient in need of such treatment an effective amount of a compound as claimed in claim 2 .
9. A method for the treatment of a disease selected from the group consisting of schizophrenia, Alzheimer's disease, Parkinson's disease, Down's syndrome, Korsakoff's alcoholic syndrome, vascular dementia, depression, anxiety, panic attack and obsessive-compulsive behavior, which comprises administering to a patient in need of such treatment an effective amount of a compound as claimed in claim 3 .