Tablets containing heat sensitive materials and method for forming thereof
The present invention provides a process and apparatus for preserving the potency of a tableted heat sensitive ingredient. The process includes the steps of forming the ingredient into a tablet and cooling the tablet for a sufficient time and at a sufficiently low temperature to decrease the heat degradation of the ingredient. The process may be carried out in any number of tablet cooling apparatus, including a conduit forming a passageway for receiving tablets from the tablet press. A coolant inlet is connected to the conduit for supplying coolant into the passageway and into contact with the tablets.
1. A tablet cooling apparatus for cooling tablets after the tablets have been formed in a tablet press having a tablet outlet, comprising:
a container having an outer surface, an inner surface, a bottom portion, and a top lid portion defining an at least partially enclosed space, wherein the top lid portion is hingedly connected to the bottom portion, wherein the enclosed space is capable of containing coolant;
wherein the container is in flow communication with the tablet outlet and is capable of receiving tablets into the enclosed space;
a coolant inlet coupled to the container for supplying coolant to the enclosed space; and
a coolant source for supplying coolant to the coolant inlet, the coolant source being in flow communication with the coolant inlet.
2. The tablet cooling apparatus of claim 1 , further including a tablet inlet, the tablet inlet passing through the container outer surface to the inner surface, wherein the tablet inlet is in flow communication with the tablet press outlet and is capable of receiving tablets.
3. The tablet cooling apparatus of claim 1 , further including a hopper for removing tablets from the container and separating coolant from the removed tablets the hopper having a bottom surface for retaining tablets and at least one aperture for releasing coolant.
4. The tablet cooling apparatus of claim 3 , wherein the hopper further includes a handle for manually lifting the hopper in and out of the container.
5. The tablet cooling apparatus of claim 3 , further including a temperature sensing device connected to the container for the detection of temperature within the enclosed space.
6. The tablet cooling apparatus of claim 3 , further including a valve, the valve being in coolant flow communication between the coolant inlet and the coolant source, and wherein the valve controls the flow of coolant to the enclosed space.
7. The tablet cooling apparatus of claim 3 , further including a temperature sensing device and a control device, the temperature sensing device being connected to the container for the detection of temperature within the enclosed space, wherein the temperature sensing device sends an output signal to the control device, the control device being associated with the valve, and wherein the control device regulates the flow of coolant to the enclosed space in response to the temperature sensing device output signal by adjusting the valve.