Soft capsule preparation
View Patent ↗A soft capsule preparation which comprises a dispersion of (2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid in a vegetable oil filled in a soft capsule comprising a shell having a light blocking effect. The soft capsule preparation preferably comprises polyoxyethylene sorbitan monooleate and glycerol monostearate and the like as surfactants. As the vegetable oil, soybean oil, sesame oil, a mixture thereof, or the like may be used.
1. A soft capsule preparation which comprises a dispersion of (2E,4E,6E,10E)-3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid in a vegetable oil comprising soybean oil, sesame oil, or a mixture thereof filled in a soft capsule comprising a shell having a light blocking effect.
2. The soft capsule preparation according to claim 1 , wherein the dispersion comprises at least one surfactant selected from glycerol monostearate, sorbitan sesquioleate, polyoxyethylene sorbitan monooleate, and sucrose fatty acid ester.
3. The soft capsule preparation according to claim 2 , wherein the at least one surfactant comprises polyoxyethylene sorbitan monooleate and glycerol monostearate.
4. The soft capsule preparation according to claim 1 , wherein the shell having the light blocking effect comprises a light blocking agent.
5. The soft capsule preparation according to claim 4 , wherein the light blocking agent is titanium oxide, yellow ferric oxide, or a mixture thereof.
6. The soft capsule preparation according to claim 1 , wherein the shell comprises of succinyl gelatin.