Granted Patent
B2
US 7,318,927 · App. 10/469,256 · Granted Jan 15, 2008
Recombinant poxvirus for chimeric proteins of the human immunodeficiency virus
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Abstract
The invention relates to HIV chimeric gene formed by the union of fragments of different genes of said virus, wherein said fragments contains epitopes for cytotoxic T cells (CTL) or HIV-1 auxiliary T cells, which are presented by a wide range of antigens of type Major Histocompatibility Complex (HLA-I). Recombinant poxviruses are obtained from said genes, which are useful for prophylactic and therapeutic vaccination against HIV/AIDS infections, are capable of generating a protective immune cell response in vaccinated laboratory animals and are recognized by the CTL lymphocytes of HIV/AIDS patients.
Claims (1)
1. A chimeric protein encoded by a nucleic acid sequence comprising SEQ. ID. NO.: 1.
Assignments (3)
CORRECTION OF IMPROPERLY RECORDED DOCUMENT
Recorded Mar 23, 2010
From: JEREZ, NILO, MR.
To: CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
Reel/Frame 024120/0426 →
JUDGMENT/LIEN/SECURITY INTEREST
Recorded Dec 8, 2009
From: CENTRO DE INGENIERA GENETICA Y BIOTECNOLOGIA
To: JEREZ, NILO, MR.
Reel/Frame 023620/0190 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 9, 2004
From: PEREZ, ENRIQUE IGLESIAS; BLOMQUIST, DANIA M. VAZQUEZ; CANO, CARLOS A. DUARTE
To: CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
Reel/Frame 014866/0153 →
Priority Claims (1)
CU 57/01
· Feb 28, 2001
· national
Continuity (1)