IP Library Granted Patent US 7,322,698
Granted Patent B2
US 7,322,698 · App. 11/432,230 · Granted Jan 29, 2008

Method for judging changes in images of the eye or its component parts

Assignee: The Trustees Of The University of Pennsylvania
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Quick Facts
Patent No.
US 7,322,698
App. No.
11/432,230
Granted
Jan 29, 2008
Kind
B2
Abstract

The invention includes a computer-implemented method, system, and computer-readable medium having computer-executable modules for judging changes in components of an eye. The inventive computer-implemented method includes the steps of acquiring, displaying, and superimposing at least two digital images of the components of the eye. The method further includes the step of processing at least one of the digital images such that the superimposed images may be compared, and the step of flickering among the superimposed digital images. The step of acquiring the images may include the step of converting a photographic representation of the components of the eye to the digital image. The step of processing may include registering, warping, and/or aligning the digital images.

Claims (33)

1. A system for judging changes in components of an eye, comprising:

a data processor that receives a pair of stereo photographic images of components of the eye, and that processes at least one of the pair of stereo photographic images to facilitate comparison among the images, said processing including at least one of (1) non-rigid, non-global deforming of the stereo photographic images, (2) global deforming of the stereo photographic images, and (3) non-global deforming of the stereo photographic images;

a display device in communication with the data processor, wherein the display device displays the stereo photographic images; and

a control unit in communication with the data processor, wherein the control unit compares the pair of stereo photographic images for detection of a change in components of the eye.

2. The system of claim 1 , wherein the control unit matches the respective photographic images of the pair of stereo photographic images of the components of the eye and uses the matched pairs for detection of a change in components of the eye.

3. A computer-implemented method of judging changes in components of an eye, comprising:

acquiring at least two different digital images of components of the eye;

superimposing the digital images on a generated display;

processing at least one of the digital images, said processing including at least one of (1) non-rigid, non-global deforming of the digital images, (2) global deforming of the digital images, and (3) non-global deforming of the digital images; and

comparing the superimposed digital images as a function of the processing for detection of a change in components of the eye.

4. The computer-implemented method of claim 3 , wherein the processing comprises registering the digital images.

5. The computer-implemented method of claim 4 , wherein the registering of the digital images comprises non-rigid, non-global deforming of the digital images.

6. The computer-implemented method of claim 3 , wherein the processing comprises warping the digital images.

7. The computer-implemented method of claim 6 , wherein the warping comprises at least one of the following: global and non-global deforming of the digital images.

8. The computer-implemented method of claim 3 , wherein the processing comprises aligning the digital images.

9. The computer-implemented method of claim 8 , wherein the aligning comprises non-rigidly aligning the digital images.

10. The computer-implemented method of claim 9 , wherein the aligning comprises rigidly aligning the digital images.

11. The computer-implemented method of claim 3 , further comprising detecting changes among the superimposed digital images.

12. The computer-implemented method of claim 3 , further comprising at least one of the following: diagnosing, documenting, and managing a condition of the eye as a function of the detected changes in components of the eye.

13. The computer-implemented method of claim 3 , wherein the acquiring of the digital images comprises converting a photographic representation of the components of the eye to the digital image.

14. The computer-implemented method of claim 3 , further comprising selecting at least two of the acquired digital images.

15. The computer-implemented method of claim 3 , further comprising flickering among the superimposed digital images.

16. A system for judging changes in components of an eye, comprising:

a data processor that receives and superimposes at least two different digital images of components of the eye, and that processes at least one of the digital images to facilitate comparison among the images, said processing including at least one of (1) non-rigid, non-global deforming of the digital images, (2) global deforming of the digital images, and (3) non-global deforming of the digital images;

a display device in communication with the data processor, wherein the display device displays the digital images and the superimposed digital images; and

a control unit in communication with the data processor, wherein the control unit compares the superimposed digital images as a function of the processing.

17. The system of claim 16 , further comprising an image scanner in communication with the data processor for converting photographic images of the components of the eye to the digital images.

18. The system of claim 16 , wherein the control unit allows for flickering among the superimposed digital images.

19. The system of claim 16 , further comprising a digital image acquisition device in communication with the data processor for acquiring the digital images.

20. The system of claim 16 , further comprising a data store in communication with the data processor for storing the digital images.

21. The system of claim 16 , wherein the digital image acquisition device comprises at least one of the following: a direct ophthalmoscope, an indirect ophthalmoscope, a slit lamp biomicroscope, and a fundus camera.

22. The system of claim 16 , wherein the digital images depict an optic nerve head component of the eye.

23. The system of claim 16 , wherein the digital images are monoscopic.

Assignments (1)
CONFIRMATORY LICENSE Recorded Jan 14, 2021
From: UNIVERSITY OF PENNSYLVANIA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 055503/0055 →
Continuity (5)
Continuation 1076160600 · Jan 21, 2004
Continuation 1016893200 · Dec 18, 2002
Continuation PCTUS003479700 · Dec 21, 2000
Provisional Application 6017151900 · Dec 22, 1999
Related Publication 20060238706A1 · Oct 26, 2006