IP Library › Granted Patent US 7,351,254
Granted Patent B2
US 7,351,254 · App. 11/003,220 · Granted Apr 1, 2008

Method and device for patient temperature control employing optimized rewarming

Assignee: Innercool Therapies, Inc.
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Quick Facts
Patent No.
US 7,351,254
App. No.
11/003,220
Granted
Apr 1, 2008
Kind
B2
Abstract

Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient's body or a selected portion thereof. In particular, strategies for optimizing the rewarming of patients for various medical procedures are provided, including stroke, neurosurgery, and myocardial infarction.

Claims (26)

1. A method of rewarming a patient following neurosurgery comprising:

draping a patient with a blanket;

inserting a heat transfer element into a vein of the patient, wherein the heat transfer element includes at least two heat transfer segments separated by a bellows;

circulating a working fluid through the heat transfer element, the working fluid heated by a heat exchanger to a temperature sufficient to raise the temperature of a blood stream to a temperature less than about 42° C.;

sensing a patient temperature;

controlling the patient temperature to a target temperature of less than about 35° C.; and

rewarming the patient to normothermia using a heating blanket, wherein the heat transfer element includes a straight lumen surrounded by a helical lumen.

2. The method of claim 1 , wherein the heat transfer element is flexible and is made of a polymer.

3. The method of claim 1 , wherein the sensing a patient temperature includes sensing a patient temperature with an esophageal probe.

4. A method of rewarming a patient following a stroke comprising:

covering a patient with a heating blanket set to a temperature of between about 38° C. and 43° C.;

inserting a heat transfer element into a vein of the patient, wherein the heat transfer element includes at least two heat transfer segments separated by a bellows;

circulating a working fluid through the heat transfer element;

sensing a patient temperature;

controlling the patient temperature such that the patient temperature rises to greater than about 36° C. over a period of time between about 6 hours to about 24 hours;

if the patient is experiencing shivering during the controlled rewarm, administering an antishivering drug; and

rewarming the patient to normothermia using the active heating blanket, wherein the heat transfer element includes a straight lumen surrounded by a helical lumen.

5. The method of claim 4 , wherein the heat transfer element is flexible and is made of a polymer.

6. A method of rewarming a patient following a cardiovascular surgery, comprising:

inserting a heat transfer element into a vein of the patient wherein the heat transfer element includes at least two heat transfer segments separated by a bellows;

performing a cardiac surgery;

following the cardiac surgery, circulating a working fluid through the heat transfer element, the working fluid heated by a heat exchanger to a temperature sufficient to raise the blood temperature to a blood temperature less than about 42° C.;

sensing a patient temperature;

controlling the patient temperature such that the patient temperature rises to greater than about 36.5° C.

7. The method of claim 6 , wherein the sensing a patient temperature includes sensing a patient temperature with an esophageal probe.

8. The method of claim 6 , wherein the sensing a patient temperature includes sensing a patient temperature with a bladder probe.

Assignments (10)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 20, 2015
From: PHILIPS ELECTRONICS NORTH AMERICA CORPORATION
To: ZOLL CIRCULATION, INC.
Reel/Frame 035054/0888 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2014
From: INNERCOOL THERAPIES, INC.
To: PHILIPS ELECTRONICS NORTH AMERICA CORPORATION
Reel/Frame 033975/0849 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2014
From: MARVIN, ROBERT
To: PHILIPS ELECTRONICS NORTH AMERICA CORPORATION
Reel/Frame 033858/0451 →
RELEASE OF SECURITY INTEREST Recorded Sep 30, 2014
From: MARSHALL, ROBERT
To: PHILIPS ELECTRONICS NORTH AMERICA CORPORATION
Reel/Frame 033859/0044 →
SECURITY AGREEMENT Recorded Mar 9, 2009
From: INNERCOOL THERAPIES, INC.
To: MARSHALL, ROBERT
Reel/Frame 022380/0013 →
SECURITY AGREEMENT Recorded Nov 5, 2008
From: INNERCOOL THERAPIES, INC.
To: MARVIN, ROBERT
Reel/Frame 021794/0394 →
RELEASE OF SECURITY INTEREST Recorded Jul 15, 2008
From: LIFE SCIENCES CAPITAL, LLC
To: INNERCOOL THERAPIES, INC.
Reel/Frame 021230/0753 →
SECURITY AGREEMENT Recorded Nov 16, 2007
From: INNERCOOL THERAPIES, INC.
To: LIFE SCIENCES CAPITAL, LLC
Reel/Frame 020125/0289 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2007
From: INNERCOOL THERAPIES, INC., A CALIFORNIA CORPORATION
To: INNERCOOL THERAPIES, INC., A DELAWARE CORPORATION
Reel/Frame 019781/0492 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 3, 2004
From: MAGERS, MICHAEL
To: INNERCOOL THERAPIES, INC.
Reel/Frame 016081/0719 →
Continuity (30)
Continuation 1021648700 · Aug 9, 2002
Continuation In Part 1008296400 · Feb 25, 2002
Continuation In Part 1011773300 · Apr 4, 2002
Continuation In Part 1000541600 · Nov 7, 2001
Continuation In Part 1000754500 · Nov 6, 2001
Continuation In Part 0988565500 · Jun 20, 2001
Continuation In Part 0980015900 · Mar 6, 2001
Continuation In Part 0979702800 · Feb 27, 2001
Continuation In Part 0978524300 · Feb 16, 2001
Continuation In Part 0975712400 · Jan 8, 2001
Continuation In Part 0971474900 · Nov 16, 2000
Continuation In Part 0965895000 · Sep 11, 2000
Continuation In Part 0965094000 · Aug 30, 2000
Continuation In Part 0962105100 · Jul 21, 2000
Continuation In Part 0960779900 · Jun 30, 2000
Continuation In Part 0956653100 · May 8, 2000
Continuation In Part 0953993200 · Mar 31, 2000
Continuation In Part 0951902200 · Mar 3, 2000
Continuation In Part 0937929500 · Aug 23, 1999
Continuation In Part 0937311200 · Aug 11, 1999
Continuation In Part 0929253200 · Apr 15, 1999
Continuation In Part 0924678800 · Feb 9, 1999
Provisional Application 6032832000 · Oct 9, 2001
Provisional Application 6032825900 · Oct 9, 2001
Provisional Application 6032294500 · Sep 14, 2001
Provisional Application 6031692200 · Aug 31, 2001
Provisional Application 6031605700 · Aug 29, 2001
Provisional Application 6031240900 · Aug 15, 2001
Provisional Application 6031158900 · Aug 9, 2001
Related Publication 20050096715A1 · May 5, 2005