IP Library Granted Patent US 7,374,943
Granted Patent B2
US 7,374,943 · App. 10/474,505 · Granted May 20, 2008

Haemoglobin assay

Assignee: Axis-Shield USA
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Quick Facts
Patent No.
US 7,374,943
App. No.
10/474,505
Granted
May 20, 2008
Kind
B2
Abstract

The invention provides a kit for a glycated haemoglobin assay, said kit comprising: a porous membrane capable of retaining precipitated haemoglobin; a first reagent comprising zinc ions in aqueous basic solution or comprising a water soluble zinc compound; a second reagent comprising a chromophore-boronic acid conjugate; and optionally, an aqueous washing reagent; wherein at least one of the first and second reagents further comprises a surfactant capable of lysing erythrocytes, and wherein said second reagent if liquid is acidic.

Claims (14)

1. A kit for a glycated haemoglobin assay, said kit comprising:

a porous membrane capable of retaining precipitated haemoglobin;

a first reagent comprising zinc ions in aqueous basic solution or comprising a water soluble zinc compound; and

a second reagent comprising a chromophore-boronic acid conjugate;

wherein at least one of the first and second reagents further comprises a surfactant capable of lysing erythrocytes, said second reagent if liquid is acidic and the boronic acid conjugate and the zinc are present in separate reagents in the assay kit.

2. A kit as claimed in claim 1 further comprising an aqueous washing agent.

3. A kit as claimed in claim 1 wherein said first reagent comprises zinc ions in aqueous basic solution.

4. A kit as claimed in claim 1 wherein said second reagent contains a surfactant.

5. A kit as claimed in claim 1 wherein said second reagent is a dried material.

6. A kit as claimed in claim 1 wherein said first reagent contains a surfactant.

7. A kit as claimed in claim 1 wherein at least one of said first and second reagents contains albumin.

8. A kit as claimed in claim 1 wherein one of said first and second reagents is in liquid form in a container and the other of said first and second reagents is in dried form coated on a stopper applicable to said container.

9. A kit as claimed in claim 1 wherein said second reagent is liquid and said first and second reagents are disposed in a two chamber container with a frangible membrane separating the chambers.

10. A kit as claimed in claim 8 wherein the reagent coated on the stopper is the second reagent and contains albumin.

Assignments (3)
CHANGE OF NAME Recorded Nov 2, 2021
From: AXIS-SHIELD ASA
To: AXIS-SHIELD AS
Reel/Frame 057998/0816 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2021
From: AXIS-SHIELD AS
To: ABBOTT RAPID DIAGNOSTICS INTERNATIONAL UNLIMITED COMPANY
Reel/Frame 058002/0251 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2004
From: HOLTLUND, JOSTEIN; BERNSTROM, KERSTIN; DWORSKY, ELLEN; CORNELIUSSEN, LISE
To: AXIS-SHIELD ASA
Reel/Frame 014894/0907 →
Priority Claims (1)
GB 0110053.6 · Apr 24, 2001 · national
Continuity (1)
Related Publication 20040137641A1 · Jul 15, 2004