IP Library › Granted Patent US 7,440,601
Granted Patent B1
US 7,440,601 · App. 10/961,681 · Granted Oct 21, 2008

Automated identification of ileocecal valve

Assignees: The United States of America as represented by the Department of Health and Human Services; Mayo Foundation for Medical Education and Research
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Quick Facts
Patent No.
US 7,440,601
App. No.
10/961,681
Granted
Oct 21, 2008
Kind
B1
Abstract

Portions of a virtual colon can be analyzed to identify a normal structure, such as an ileocecal valve. Paradigmatic characteristics of ileocecal valves can be used to identify a digital representation as an ileocecal valve. Upon determination that a digital representation has the characteristics of an ileocecal valve, action can be taken. For example, the digital representation can be removed from a list of polyp candidates.

Claims (73)

1. A computer-implemented method of processing a digital representation of at least a portion of a colon, the method comprising:

receiving one or more characteristics of the digital representation of at least a portion of a colon;

in software, determining whether the characteristics of the digital representation comprise characteristics of an ileocecal valve; and

based on said determining whether the characteristics of the digital representation comprise characteristics of an ileocecal valve, taking an action with respect to the digital representation.

2. A computer-readable medium comprising computer-executable instructions for performing a method of processing a digital representation of at least a portion of a colon, the method comprising:

receiving one or more characteristics of the digital representation of at least a portion of a colon;

in software, determining whether the characteristics of the digital representation comprise characteristics of an ileocecal valve; and

based on said determining whether the characteristics of the digital representation comprise characteristics of an ileocecal valve, taking an action with respect to the digital representation.

3. The method of claim 1 wherein the digital representation is acquired via imaging.

4. The method of claim 1 wherein the digital representation is acquired via Computed Tomography Imaging technology.

5. The method of claim 1 wherein the digital representation is acquired via MRI technology.

6. The method of claim 1 wherein the digital representation is acquired via ultrasound technology.

7. The computer-implemented method of claim 1 wherein boundaries of the digital representation are determined via a segmentation technique.

8. The computer-implemented method of claim 1 wherein the receiving takes place after having classified the digital representation as a polyp candidate with a software classifier.

9. The computer-implemented method of claim 8 wherein the action comprises declassifying the digital representation as a polyp candidate.

10. The method of claim 8 wherein the polyp candidates are discovered via surface based filters measuring regions in the digital representation.

11. The method of claim 10 wherein the surface-based filtering criteria detects polyps based on at least the following criteria:

elliptical curvature subtype;

curvature range;

number of vertices;

diameter; and

sphericity.

12. The method of claim 8 wherein the polyp candidates are discovered via segmentation.

13. The method of claim 8 wherein boundaries of polyp candidates are discovered via segmentation.

14. The method of claim 13 wherein the segmentation is operable to segment a structure of the digital representation having the following characteristics:

a boundary between the structure and a lumen of the colon is convex;

the structure is of at least a minimum size; and

the structure is not flat.

15. The computer-implemented method of claim 1 wherein the action comprises removing the digital representation from a list of polyp candidates.

16. The computer-implemented method of claim 1 wherein the action comprises distinctively depicting the digital representation in a visual depiction thereof.

17. The computer-implemented method of claim 1 wherein the characteristics of the ileocecal valve comprise volume.

18. The method of claim 17 wherein volume of the digital representation is determined via an interior of boundaries of the digital representation.

19. The computer-implemented method of claim 1 wherein the characteristics of the ileocecal valve comprise density.

20. The computer-implemented method of claim 19 wherein the characteristics of the ileocecal valve further comprise volume.

21. The method of claim 19 wherein density of the digital representation is determined via an entire segmented area of the digital representation.

22. The method of claim 19 wherein density of the digital representation is determined via an interior of boundaries of the digital representation.

23. The method of claim 19 wherein density of the digital representation is determined via an average of an entire segmented area of the digital representation.

24. The method of claim 19 wherein density of the digital representation is determined by attenuation of the digital representation.

25. The method of claim 24 wherein the attenuation of the digital representation is determined via an interior of boundaries of the digital representation.

26. The method of claim 24 wherein the attenuation of the digital representation is determined via an average of an entire segmented area of the digital representation.

27. The computer-implemented method of claim 1 wherein the characteristics of the ileocecal valve comprise location within the colon.

28. The computer-implemented method of claim 1 wherein the characteristics of the ileocecal valve comprise intensity.

29. The computer-implemented method of claim 1 wherein the characteristics of the ileocecal valve comprise attenuation.

30. The computer-implemented method of claim 1 wherein the digital representation represents a lipoma.

31. The computer-implemented method of claim 1 wherein the digital representation represents an ileocecal valve.

32. The computer-implemented method of claim 1 further comprising:

confirming the digital representation represents an ileocecal valve by identifying a digital representation of gas proximate to the digital representation.

33. A computer-implemented method of processing a digital representation of a portion of an anatomical structure, the method comprising:

out of a set of digital representations of a plurality of portions of the anatomical structure, identifying one digital representation out of the digital representations as a normal structure in software, wherein the set of digital representations is a product of a software classifier identifying the set of digital representations as polyp candidates within a digital representation of the anatomical structure, wherein identifying the one digital representation is based on at least density and volume associated with the digital representation; and

responsive to identifying the one digital representation as a normal structure, designating the one digital representation as not being a polyp candidate;

wherein:

the anatomical structure comprises a colon; and

the normal structure comprises an ileocecal valve.

34. A computer-based classifier for processing a digital representation of at least a portion of a colon, the classifier comprising:

stored ileocecal valve characteristics, the stored characteristics representing paradigmatic characteristics of digital representations of ileocecal valves; and

a comparer operable to compare the stored ileocecal valve characteristics with those of the digital representation of at least a portion of a colon, the comparer further operable to indicate whether the digital representation has the characteristics.

35. The classifier of claim 34 wherein the classifier is further operable to remove the portion from a list of polyp candidates when the portion meets the thresholds.

36. The classifier of claim 34 wherein the classifier is further operable to identify a lipoma.

37. The classifier of claim 34 wherein:

the classifier is part of a computer-aided detection system for locating polyps within the colon; and

the classifier performs segmentation, including segmentation of the digital representation;

wherein the digital representation represents an ileocecal valve.

38. A computer-based classifier for processing a digital representation of at least a portion of a colon, the classifier comprising:

means for storing stored ileocecal valve characteristics, the stored characteristics representing paradigmatic characteristics of digital representations of ileocecal valves; and

means for comparing the stored ileocecal valve characteristics with those of the digital representation of at least a portion of a colon, the means for comparing further operable to indicate whether the digital representation has the characteristics of an ileocecal valve.

39. A computer-implemented method of depicting a virtual anatomical structure, the method comprising:

receiving a virtual colon;

in software comprising a comparer configured to compare one or more ileocecal valve characteristics with characteristics of at least a portion of the virtual colon, processing the virtual colon to detect an ileocecal valve; and

presenting the ileocecal valve distinctively in a presentation of at least a portion of the virtual colon.

40. A computer-generated user interface for presenting a graphical representation of an anatomical structure, the user interface comprising:

a depiction of the anatomical structure;

wherein a region of the anatomical structure detected as an ileocecal valve by software is depicted distinctively after detection by software comprising a comparer configured to compare one or more ileocecal valve characteristics with characteristics of the region of the anatomical structure.

41. The computer-generated user interface of claim 40 wherein the region is depicted with a distinctive color.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2017
From: SHARP KABUSHIKI KAISHA
To: DOLBY LABORATORIES LICENSING CORPORATION
Reel/Frame 043101/0675 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 5, 2008
From: JOHNSON, C. DANIEL
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 021055/0430 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 7, 2005
From: SUMMERS, RONALD, M.D., PH.D.; YAO, JIANHUA, PH.D.
To: THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRENSENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICE, THE
Reel/Frame 015570/0609 →
Continuity (2)
Continuation In Part 1077921000 · Feb 13, 2004
Provisional Application 6051064000 · Oct 10, 2003