Nematode phosphoethanolamine N-methyltransferase-like sequences
Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
1. A purified polypeptide comprising an amino acid sequence that is at least 95% identical to the amino acid sequence of SEQ ID NO:9, wherein the polypeptide has methyltransferase activity.
2. The purified polypeptide of claim 1 , wherein the amino acid sequence is at least 98% identical to the amino acid sequence of SEQ ID NO:9, wherein the polypeptide has methyltransferase activity.
3. A purified polypeptide comprising the amino acid sequence of SEQ ID NO:9.