IP Library Granted Patent US 7,563,575
Granted Patent B2
US 7,563,575 · App. 11/439,114 · Granted Jul 21, 2009

Breeding and milking cows for milk free of β-casein A

Assignee: A2 Corporation Limited
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Quick Facts
Patent No.
US 7,563,575
App. No.
11/439,114
Granted
Jul 21, 2009
Kind
B2
Abstract

A milk or other dairy product, capable of minimising the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the β-casein A 1 allele. Bulk milk can be produced by testing for and culling cows who test positive for the β-casein A 1 allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the β-casein A 1 allele, or other commercial, milk producing animals, to this allele, to counteract the immunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.

Claims (9)

1. A method for breeding a bovine cow or bull whose genomes encode for the production of milk containing β-casein A 2 , A 3 , B, C, D, or E but substantially free of β-casein A 1 , comprising:

inseminating a bovine cow that has been tested and identified as having a genome that encodes for the production of milk containing β-casein A 2 , A 3 , B, C, D, or E but substantially free of β-casein A 1

with semen from a bovine bull where that bull has been tested and identified as a genome that encodes for the production of milk containing β-casein A 2 , A 3 , B, C, D, or E but substantially free of β-casein A 1 .

2. The method according to claim 1 , wherein said cow and bull both have genomes that encode for the production of β-casein A 2 .

3. The method according to claim 1 , wherein said cow and bull both are Bos taurus bovines.

4. The method according to claim 1 , wherein said cow is artificially inseminated.

5. The method according to claim 1 , wherein said cow is tested by testing DNA obtained from the blood, hair, or skin of said cow.

6. The method according to claim 1 , wherein said bull is tested by testing DNA obtained from the semen, blood, hair, or skin of said bull.

7. The method according to claim 1 , wherein said bull is tested by testing DNA obtained from the semen of said bull.

Assignments (3)
CHANGE OF NAME Recorded Nov 13, 2014
From: A2 CORPORATION LIMITED
To: THE A2 MILK COMPANY LIMITED
Reel/Frame 034229/0619 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 24, 2006
From: MCLACHLAN, CORRAN NORMAN STUART
To: MACHIN INVESTMENTS LIMITED
Reel/Frame 017930/0239 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 24, 2006
From: MACHIN INVESTMENTS LIMITED
To: A2 CORPORATION LIMITED
Reel/Frame 017930/0251 →
Priority Claims (1)
NZ 272133 · May 16, 1995 · national
Continuity (5)
Division 1036967900 · Feb 21, 2003
Continuation In Part 0990661400 · Jul 18, 2001
Continuation 0950080100 · Feb 10, 2000
Continuation 0864521900 · May 13, 1996
Related Publication 20060265768A1 · Nov 23, 2006