IP Library Granted Patent US 7,588,783
Granted Patent B2
US 7,588,783 · App. 10/581,494 · Granted Sep 15, 2009

Flavonoid derivative

Assignee: Merck Patent GmbH
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Quick Facts
Patent No.
US 7,588,783
App. No.
10/581,494
Granted
Sep 15, 2009
Kind
B2
Abstract

The invention relates to a novel flavonoid derivative, to an extract comprising the flavonoid derivative, to the cosmetic and pharmaceutical use thereof, to preparations comprising the flavonoid derivative or extract, and to a process for the preparation of the flavonoid derivative or extract.

Claims (18)

1. The compound [5-Hydroxy-7-methoxy-2-(4′-methoxyphenyl)-4-oxo-4H-chromen-8-yl]sulfonic acid monoester, or a physiologically acceptable salt or solvate thereof, in substantially isolated form.

2. A composition comprising the substantially isolated compound according to claim 1 and optionally excipients and/or adjuvants.

3. A composition according to claim 2 , in a medicament form.

4. A composition according to claim 2 , in a cosmetic composition form.

5. A composition according to claim 3 , in a skin-treatment composition form.

6. A composition in a form for topical use comprising:

a) the substantially isolated compound according to claim 1 ,

b) a skin-tolerated excipient, and

c) optionally one or more further active ingredients having a skin-care and/or inflammation-inhibiting action.

7. A composition according to claim 5 , which furthermore comprises one or more UV filters.

8. A composition according to claim 2 , which comprises one or more further antioxidant(s).

9. A composition according to claim 2 , which comprises one or more further compound(s) selected from the group of the flavonoids and/or coumaranones.

10. A food which is enriched with the substantially isolated compound according to claim 1 .

11. A food supplement which comprises the substantially isolated compound according to claim 1 .

12. A process for the preparation of the compound according to claim 1 which comprises extracting from plant material of the species Sidastrum acuminatum, Sidastrum - bufferense, Sidastrum E.G. Baker, Sidastrum - kicranthum, Sidastrum lodiegense, Sidastrum multiflorum, Sidastrum micranthum, Sidastrum paniculatum, Sidastrum strictum, Sidastrum tehuacanum or Sidastrum quinquenervium , to provide an extract and obtaining the compound in substantially isolated form therefrom.

13. Process according to claim 12 , characterised in that the plant material used is Sidastrum micranthum.

14. A method for preparing a cosmetic composition, a pharmaceutical composition, a food and/or a food supplement which comprises combining a compound according to claim 1 with at least one excipient suitable for a cosmetic, at least one excipient suitable for a pharmaceutical, at least one food or at least one excipient suitable for a food supplement.

15. A method for increasing the resistance of the skin to environmental influences, for increasing resistance of the skin to drying out, for treating skin ageing, for improving the skin structure, and/or for improving the formation of smooth skin which comprises topically apply to the skin a composition comprising the substantially isolated compound of claim 1 .

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2012
From: MERCK PATENT GMBH
To: EUROPEAN BRAND PARTICIPATIONS SA
Reel/Frame 028968/0086 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 2, 2006
From: BUCHHOLZ, HERWIG; WIRTH, CORINNA; CAROLA, CHRISTOPHE; ALVES FONTES, ROSANE
To: MERCK PATENT GMBH
Reel/Frame 017986/0762 →
Priority Claims (1)
DE 103 57 004 · Dec 5, 2003 · national
Continuity (1)
Related Publication 20070134172A1 · Jun 14, 2007