4,5-dihydro-1H-pyrazole derivatives having potent CB
The present invention relates to a group of novel 4,5-dihydro-1H-pyrazole derivatives which are potent cannabinoid (CB 1 ) receptor antagonists with utility for the treatment of diseases connected with disorders of the cannabinoid system. The compounds have the general formula (Ia) or (Ib) wherein the symbols have the meanings given in the specification. The invention also relates to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these compounds as an active component.
1. A compound of formula (I):
2. A pharmaceutical composition comprising a pharmaceutically effective amount of a compound of formula (I), as claimed in claim 1 , and at least one auxiliary substance, liquid carrier material, or solid carrier material, or a mixture of two or more of the foregoing.