IP Library Granted Patent US 7,618,376
Granted Patent B2
US 7,618,376 · App. 11/924,862 · Granted Nov 17, 2009

Device for assessing perfusion failure in a patient by measurement of blood flow

Assignee: Vasamed, Inc.
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Quick Facts
Patent No.
US 7,618,376
App. No.
11/924,862
Granted
Nov 17, 2009
Kind
B2
Abstract

A device is provided for assessing impairment of blood circulation in a patient, such as that in perfusion failure, by measurement of blood flow adjacent a mucosal surface accessible by a mouth or nose and connecting with the gastrointestinal tract or upper respiratory/digestive tract of a patient. The device includes a blood-flow sensor adapted to be positioned adjacent a mucosal surface with a patient's body and measuring blood flow in adjacent tissue and a PCO.sub.2 sensor adapted to be positioned adjacent the mucosal surface and measuring PCO.sub.2. In addition a pH sensor may be used in combination with the blood flow determination. A method of detecting perfusion failure is also disclosed. The method includes utilizing blood-flow measurements in conjunction with a surface perfusion pressure index and/or an optical plethysmography index to more accurately assess perfusion failure. These measurements may also be supplement by taking measurements of pH, sublingual PCO.sub.2, and Sa O.sub.2. The invention affords rapid measurement and detection of perfusion failure.

Claims (17)

1. A device for assessing the degree of systemic perfusion in a patient, the device comprising:

a. a surface perfusion pressure monitor for measuring the surface perfusion pressure of a patient; and

b. a blood pressure monitor for measuring the blood pressure of the patient;

wherein the device derives an index from the surface perfusion pressure measurement and the blood pressure measurement to assess the degree of systemic perfusion of the patient.

2. The device of claim 1 , wherein the surface perfusion pressure monitor includes a laser Doppler sensor.

3. The device of claim 2 wherein the index derived is a surface perfusion pressure index.

4. The device of claim 1 wherein the surface perfusion pressure monitor includes a photoplethysmograph.

5. The device of claim 4 wherein the index derived is an optical plethysmography index.

6. The device of claim 1 further comprising a blood flow sensor adapted to be positioned adjacent a mucosal surface within a patient's body for taking a measurement, directly or indirectly, the measurement selected from the group consisting of sublingual PCO 2 , and SaO 2 .

7. The device of claim 6 further comprising a sensor for measuring pH.

8. A method for assessing the degree of systemic perfusion in a patient comprising the steps of (i) measuring the surface perfusion pressure in the patient by utilizing a surface perfusion pressure monitor; (ii) measuring blood pressure in the patient; (iii) calculating an index with a processor derived from the surface perfusion pressure measurement and the blood pressure measurement; and (iv) assessing the degree of systemic perfusion of the patient.

9. The method of claim 8 wherein the step of measuring the surface perfusion pressure in a patient includes taking the measurement with a laser Doppler sensor.

10. The method of claim 9 wherein the step of calculating an index derived from the surface perfusion pressure measurement and the blood pressure measurement includes calculating a surface perfusion pressure index.

11. The method of claim 8 wherein the step of measuring the surface perfusion pressure in a patient includes taking the measurement with a photoplethysmograph.

12. The method of claim 11 wherein the step of calculating an index derived from the surface perfusion pressure measurement and the blood pressure measurement includes calculating an optical plethysmography index.

13. The method of claim 8 further comprising the step of (v) taking a blood flow measurement adjacent a mucosal surface accessible by a mouth within a patient's body selected from the group consisting of sublingual PCO 2 and SaO 2 .

14. The method of claim 13 further comprising the step of (vi) providing a pH sensor for measuring pH.

Assignments (3)
NOTICE OF LICENSE Recorded May 16, 2013
From: VASAMED, INC.
To: EXOSTAT MEDICAL, INC.
Reel/Frame 030428/0352 →
CHANGE OF NAME Recorded Jul 24, 2009
From: OPTICAL SENSORS INCORPORATED
To: VASAMED, INC.
Reel/Frame 023005/0802 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2008
From: KIMBALL, VICTOR E.
To: OPTICAL SENSORS INCORPORATED
Reel/Frame 020378/0190 →
Continuity (2)
Division 1066875000 · Sep 23, 2003
Related Publication 20080103378A1 · May 1, 2008