Enteric medicinal composition for oral use
An enteric medicinal composition comprising a drug ingredient, pectin, alginic acid, or a derivative thereof, and water is provided that is easy to swallow.
1. An enteric medicinal composition, comprising a drug ingredient, pectin, alginic acid or derivative thereof, and water,
wherein the enteric medicinal composition is a gel,
a total content of the pectin and the alginic acid or derivative thereof is from 0.1 to 10% by mass in a total amount of the enteric medicinal composition,
a ratio of the alginic acid or derivative thereof to the pectin is from 0.2 to 5,
the alginic acid or derivative thereof is alginic acid, sodium alginate, calcium alginate, potassium alginate, or ammonium alginate,
the enteric medicinal composition is free both from disintegration and from releasing the drug ingredient at pH 1.2 for 120 minutes, and
the drug ingredient is eluted at pH 6.8.
2. The enteric medicinal composition according to claim 1 , wherein the drug ingredient is salazosulfapyridine.
3. The enteric medicinal composition according to claim 1 , wherein a content of the drug ingredient is from 0.01 to 40% by mass in the total amount of the medicinal composition.
4. The enteric medicinal composition according to claim 1 , wherein the alginic acid or derivative thereof is sodium alginate.
5. The enteric medicinal composition according to claim 1 , wherein the total content of the pectin and the alginic acid or derivative thereof is from 0.2 to 2% by mass in the total amount of the medicinal composition.
6. The enteric medicinal composition according to claim 1 , wherein the ratio of the alginic acid or derivative thereof to the pectin is from 0.4 to 2.5.