Methods of using rapid-onset selective serotonin reuptake inhibitors for treating sexual dysfunction
Methods for the prevention, treatment, or management of sexual dysfunction, such as premature ejaculation, by administering to a patient in need of therapy a therapeutically effective amount of a rapid-onset selective serotonin reuptake inhibitor on an as-needed basis shortly before sexual activity.
1. A method of treating or managing sexual dysfunction in a mammal in need of treatment which comprises administering on an as-needed basis to the mammal a therapeutically effective amount of dapoxetine or a pharmaceutically acceptable salt thereof, wherein the sexual dysfunction is premature ejaculation, wherein the mammal is a human male, and wherein said administration of dapoxetine is effective for treating or managing premature ejaculation in the absence of priming doses.
2. The method of claim 1 , wherein dapoxetine is administered immediately prior to, to about 12 hours prior to a sexual activity.
3. The method of claim 1 , wherein dapoxetine is administered immediately prior to, to about 8 hours prior to a sexual activity.
4. A method of treating or managing sexual dysfunction in a mammal in need of treatment which comprises administering on an as-needed basis to the mammal a therapeutically effective amount of dapoxetine or a pharmaceutically acceptable salt thereof, wherein the sexual dysfunction is premature ejaculation, wherein the mammal is a human male, wherein dapoxetine is administered immediately prior to, to about 4 hours prior to a sexual activity and wherein said administration of dapoxetine is effective for treating or managing premature ejaculation in the absence of priming doses.
5. The method of claim 1 , wherein dapoxetine is administered immediately prior to, to about 3 hours prior to a sexual activity.
6. The method of claim 1 , wherein dapoxetine is administered immediately prior to a sexual activity.
7. A method of treating premature ejaculation in a human male which comprises administering orally to the human male about 0.01 mg to about 200 mg of dapoxetine or a pharmaceutically acceptable salt thereof immediately prior to, to about 4 hours prior to a sexual activity, wherein said administration of dapoxetine is effective for treating premature ejaculation in the absence of priming doses.
8. A method of treating premature ejaculation in a human male which comprises administering orally to the human male about 0.01 mg to about 200 mg of dapoxetine or a pharmaceutically acceptable salt thereof immediately prior to, to about 3 hours prior to a sexual activity, wherein said administration of dapoxetine is effective for treating premature ejaculation in the absence of priming doses.
9. A method of treating premature ejaculation in a human male which comprises administering orally to the human male about 0.01 mg to about 200 mg of dapoxetine or a pharmaceutically acceptable salt thereof about 30 minutes to about 3 hours prior to a sexual activity, wherein said administration of dapoxetine is effective for treating premature ejaculation in the absence of priming doses.
10. A method of treating premature ejaculation in a human male which comprises administering orally to the human male about 0.01 mg to about 200 mg of dapoxetine or a pharmaceutically acceptable salt thereof immediately prior to a sexual activity, wherein said administration of dapoxetine is effective for treating premature ejaculation in the absence of priming doses.