Intravascular stent for treating vulnerable plaque and method of use
An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for rupturing a fibrous cap to controllably release vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by links. The stent includes struts and links of varying strengths about the circumference of the stent. The weaker struts and links require less force to open and, hence, may apply more stress to rupture the fibrous cap while the stronger struts and links protect the healthy portions of the body lumen. In another embodiment, the stent may include stress concentrators positioned on outer surfaces of the links. The stress concentrators are aligned with the fibrous cap prior to stent expansion so that upon stent expansion, the stress concentrators induce stress to rupture the fibrous cap, thereby releasing the vulnerable plaque.
1. An intravascular stent for use in a body lumen, comprising:
a plurality of cylindrical rings, each ring having a pattern of struts and being aligned along a common longitudinal axis of the stent;
a plurality of links interconnecting adjacent cylindrical rings;
the struts and links having variable thickness about a circumference of the stent;
a first side of the circumference of the stent;
a second side of the circumference of the stent;
wherein the struts and links of the first side of the stent are relatively stronger than the struts and links of the second side of the stent; and
one or more stress concentrators aligned along said second side while said first side is devoid of any stress concentrators.
2. The stent of claim 1 , wherein the struts and links of the first side of the stent are larger than the struts and links of the second side of the stent.
3. The stent of claim 1 , wherein the stent is balloon expandable.
4. The stent of claim 1 , wherein at least a portion of the stent includes a coating of a drug or therapeutic agent.
5. An intravascular stent for use in a body lumen, comprising:
a plurality of cylindrical rings, each ring having a pattern of struts and being aligned along a common longitudinal axis of the stent and defining a stent circumference;
a plurality of links interconnecting adjacent cylindrical rings;
a first side of the circumference of the stent;
a second side of the circumference of the stent;
wherein the struts and links of the first side of the stent circumference are relatively stronger than the struts and links of the second side of the stent circumference; and
one or more stress concentrators aligned along said second side while said first side is devoid of any stress concentrators.
6. The stent of claim 5 , wherein the struts and links have a variable thickness about the circumference of the stent.
7. The stent of claim 5 , wherein the struts and links have variable width about the circumference of the stent.
8. The stent of claim 5 , wherein the struts and links of the first side of the stent are relatively larger than the struts and links of the second side of the stent.
9. The stent of claim 5 , wherein the second side of the stent is expandable preferentially over the first side of the stent.
10. The stent of claim 5 , wherein the stent is balloon expandable.
11. The stent of claim 5 , wherein at least a portion of the stent includes a coating of a drug or therapeutic agent.
12. A dilatation system, comprising:
an intravascular stent for use in a body lumen having a plurality of cylindrical rings, each ring having a pattern of struts and being aligned along a common longitudinal axis of the stent and defining a stent circumference;
a plurality of links interconnecting adjacent cylindrical rings;
a first side of the circumference of the stent;
a second side of the circumference of the stent;
one or more stress concentrators aligned along said second side while said first side is devoid of any stress concentrators;
wherein the struts and links of the first side of the stent are relatively stronger than the struts and links of the second side of the stent;
wherein the stent is self-contracting; and
a catheter assembly including an expandable member;
wherein the stent is mounted onto the expandable member.