IP Library › Granted Patent US 7,763,254
Granted Patent B2
US 7,763,254 · App. 10/853,807 · Granted Jul 27, 2010

Human immunodeficiency virus integrase-LEDGF p75 isoform protein-protein interactions

Assignee: Cellvir
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Quick Facts
Patent No.
US 7,763,254
App. No.
10/853,807
Granted
Jul 27, 2010
Kind
B2
Abstract

The present invention relates to protein-protein interactions involved in AIDS. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, Selected Interacting Domains (SID®) which are identified due to the protein-protein interactions, methods for screening drugs for agents which modulate the interaction of proteins and pharmaceutical compositions that are capable of modulating the protein-protein interactions.

Claims (1)

1. An isolated and purified HIV integrase/p75 isoform complex, wherein the HIV integrase has a selected interacting domain having a sequence designated as SEQ ID NO.: 130, and the p75 isoform has a selected interacting domain comprising amino acids 341-507 thereof.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2017
From: LABORATOIRE BIODIM
To: HIVIH
Reel/Frame 041075/0861 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE IDENTITY OF ONE OF THE CO-OWNERS, INSERM-TRANSFERT SA PREVIOUSLY RECORDED ON REEL 029547 FRAME 0675. ASSIGNOR(S) HEREBY CONFIRMS THE CORRECT CO-OWNER SHOULD BE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM). Recorded Feb 4, 2014
From: CELLVIR
To: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (20 PERCENT INTEREST); UNIVERSITE PARIS DESCARTES (10 PERCENT INTEREST); INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (20 PERCENT INTEREST)
Reel/Frame 032157/0178 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2012
From: CELLVIR
To: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (20 PERCENT INTEREST); PARIS DESCARTES UNIVERSITY (10 PERCENT INTEREST); INSERM-TRANSFERT S.A. (20 PERCENT INTEREST)
Reel/Frame 029547/0675 →
MERGER Recorded Jan 21, 2011
From: CELLVIR
To: LABORATOIRE BIODIM
Reel/Frame 025697/0840 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2007
From: HYBRIGENICS S.A.
To: CELLVIR
Reel/Frame 018953/0459 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2005
From: LEGRAIN, PIERRE; RAIN, JEAN-CHRISTOPHE; BENAROUS, RICHARD; EMILIANI, STEPHANE; BERLIOZ-TORRENT, CLARISSA; BLOT, GUILLAUME
To: HYBRIGENICS
Reel/Frame 015760/0719 →
Continuity (4)
Continuation PCTEP021386800 · Nov 26, 2002
Provisional Application 6033334600 · Nov 26, 2001
Provisional Application 6038513200 · May 31, 2002
Related Publication 20060034860A1 · Feb 16, 2006