ALS-specific peptide composition
The invention relates to a composition for eliciting an immune response in an animal to produce an antibody that binds selectively to an amyotrophic lateral sclerosis (ALS)-specific epitope.
1. A composition for eliciting an immune response in an animal to produce an antibody that binds selectively to an amyotrophic lateral sclerosis (ALS)-specific epitope, the composition comprising an effective amount of the isolated ALS-specific epitope in admixture with a suitable diluent or carrier, wherein the ALS-specific epitope is an isolated peptide consisting of the amino acid sequence NPLSRKHGGPKDEE (SEQ ID NO:2).
2. The composition of claim 1 , further comprising an adjuvant.
3. The composition of claim 2 , wherein the epitope is conjugated to a molecule that enhances immunogenicity of the epitope.
4. The composition of claim 3 , wherein the molecule comprises keyhole limpet hemocyanin.