IP Library › Granted Patent US 7,786,141
Granted Patent B2
US 7,786,141 · App. 11/359,960 · Granted Aug 31, 2010

Dihydrospiroindene modulators of muscarinic receptors

Assignee: Vertex Pharmaceuticals Incorporated
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Quick Facts
Patent No.
US 7,786,141
App. No.
11/359,960
Granted
Aug 31, 2010
Kind
B2
Abstract

The present invention relates to dihydrospiroindene modulators of muscarinic receptors. The present invention also provides compositions comprising such dihydrospiroindene modulators, and methods therewith for treating muscarinic receptor mediated diseases.

Claims (97)

1. A compound selected from:

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2. A pharmaceutical composition comprising a compound selected from:

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and a pharmaceutical carrier.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Oct 14, 2016
From: MACQUARIE US TRADING LLC
To: VERTEX PHARMACEUTICALS INCORPORATED; VERTEX PHARMACEUTICALS (SAN DIEGO) LLC
Reel/Frame 040357/0001 →
SECURITY INTEREST Recorded Jul 10, 2014
From: VERTEX PHARMACEUTICALS INCORPORATED; VERTEX PHARMACEUTICALS (SAN DIEGO) LLC
To: MACQUARIE US TRADING LLC
Reel/Frame 033292/0311 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2006
From: MAKINGS, LEWIS R.; BLANCO, MIGUEL GARCIA-GUZMAN; HURLEY, DENNIS J.; DRUTU, IOANA; RAFFAI, GABRIEL; BERGERON, DANIELE M.; NAKATANI, AKIKO; TERMIN, ANDREAS P.; SILINA, ALINA
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 018373/0759 →
Continuity (3)
Continuation In Part 1120838600 · Aug 19, 2005
Provisional Application 6060273100 · Aug 19, 2004
Related Publication 20070043023A1 · Feb 22, 2007