Sulfotransferase 1E1 sequence variants
View Patent ↗Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
1. An isolated nucleic acid molecule consisting of: (a) twenty to 100 contiguous nucleotides of SEQ ID NO: 6, wherein said sequence includes the nucleotide at position 201 of SEQ ID NO: 6, with the proviso that the nucleotide at position 201 is thymine; or (b) the complement of (a).
2. A vector comprising the nucleic acid molecule of claim 1 .
3. An article of manufacture comprising a substrate, wherein said substrate comprises the isolated nucleic acid molecule of claim 1 .
4. An isolated nucleic acid molecule consisting of: (a) twenty to 100 contiguous nucleotides of SEQ ID NO: 6, wherein said sequence includes the nucleotide at position 201 of SEQ ID NO: 6, with the proviso that the nucleotide at position 201 is thymine; or (b) the complement of (a), and, with respect to a) or b), a label.
5. The isolated nucleic acid molecule of claim 4 , wherein said label is a fluorescent moiety.
6. The isolated nucleic acid molecule of claim 4 , wherein said label is biotin.
7. A vector comprising the nucleic acid molecule of claim 4 .
8. An article of manufacture comprising a substrate, wherein said substrate comprises the isolated nucleic acid molecule of claim 4 .