IP Library Granted Patent US 7,807,474
Granted Patent B2
US 7,807,474 · App. 11/690,193 · Granted Oct 5, 2010

System and method for direct digitization of NMR signals

Assignee: MCW Research Foundation, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,807,474
App. No.
11/690,193
Granted
Oct 5, 2010
Kind
B2
Abstract

A magnetic resonance imaging (MRI) system includes a transmitter that produces an RF excitation pulse that is applied to a subject positioned in the MRI system to induce emission of at least one of an NMR signal and an ESR signal therefrom, and that produces a reference signal indicative of the phase of the RF excitation pulse. A first analog-to-digital converter has an input for receiving the reference signal that is synchronous with the RF excitation pulse. One or more additional analog-to-digital converters/processors have inputs for receiving the at least one of NMR signals and ESR signals produced by a subject placed in the MRI system and produce one or more complex digital signals therefrom. A normalizer is connected to receive and normalize the digital reference signal and a mixer is connected to receive the normalized digital reference signal and the digital signal. Accordingly, the mixer is operable to multiply the normalized complex digital reference signal with the complex digital signal.

Claims (10)

1. A method of processing an NMR signal received by a coil, the method comprising steps of:

(A) directly digitizing the NMR signal received by the coil without down-converting the NMR signal to a frequency below the Larmor frequency;

(B) receiving and digitizing a reference signal from an MRI system, the reference signal indicating a phase of an RF excitation pulse produced by the MR system to induce the NMR signal;

(C) normalizing the digitized reference signal; and

(D) mixing the normalized digital reference signal with the digitized NMR signal.

2. The method of claim 1 further comprising adjusting at least one of steps (A) through (D) to compensate for one of a plurality of MR imaging frequencies and reference signals specific to one of the plurality of MRI systems.

3. The method of claim 1 wherein step (D) includes mixing the digitized reference signal and the digitized NMR signal to generate a phase-accurate array of NMR data.

4. The method of claim 1 wherein steps (C) and (D) are performed by a processor executing a computer program stored on a computer readable storage medium.

5. The method of claim 1 wherein step (D) includes mixing a complex conjugate of the digitized reference signal with the digitized NMR signal to generate a phase-accurate array of NMR data that can be used to reconstruct one of a two-dimensional (2D) image and a three-dimensional (3D) image.

6. The method of claim 1 wherein step (A) further includes directly digitizing the NMR signal using a plurality of additional analog-to-digital converters and producing respective complex digital NMR signals therefrom and wherein step (D) further includes mixing the normalized digital reference signal with each digital NMR signal produced by the plurality of analog-to-digital converters.

Assignments (3)
CHANGE OF NAME Recorded Jan 29, 2014
From: MCW RESEARCH FOUNDATION, INC., THE
To: THE MEDICAL COLLEGE OF WISCONSIN, INC.
Reel/Frame 032075/0358 →
CONFIRMATORY LICENSE Recorded Oct 31, 2008
From: MEDICAL COLLEGE OF WISCONSIN
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021768/0448 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2007
From: JESMANOWICZ, ANDRZEJ
To: THE MCW RESEARCH FOUNDATION, INC.
Reel/Frame 019054/0994 →
Continuity (2)
Provisional Application 6074373900 · Mar 24, 2006
Related Publication 20070224698A1 · Sep 27, 2007