Ocular imaging

1. A diagnostic light scattering method comprising:

transmitting a pencil beam of light into a subject's eye;

acquiring light from the pencil beam scattered by the subject's eye; and

analyzing the acquired scattered light to determine a location of a reference point corresponding to an interface of a lens capsule of the eye;

the analyzing to determine the reference point comprising evaluating intensity of light scattered by the eye to determine first and second regions of high intensity along a line of propagation of the pencil beam, the first and second regions being separated by a relatively large third region substantially free of scattered light from the pencil beam, the second region being further along the line of propagation from a source of the pencil beam, the second region being determined to correspond to the lens capsule.

2. The method of claim 1 wherein the analyzing comprises determining the reference point as a point corresponding to one of an interface between the lens capsule and an anterior chamber of the eye, a posterior lens capsule interface, an air-cornea interface, a cornea-aqueous interface, and an interface of a retina of the eye.

3. The method of claim 1 wherein the analyzing further comprises determining locations of a cortex, a supra-nucleus, and a nucleus of the eye.

4. The method of claim 1 further comprising:

analyzing intensity of light scattered from a portion of the eye, the portion of the eye being selected relative to the reference point, the analyzing being to determine a physical property of material at the selected portion; and

providing an indication of the physical property of the material at the selected portion.

5. The method of claim 4 wherein providing the indication comprises providing an indication of presence of aggregates in a supra-nucleus of the eye.

6. The method of claim 1 further comprising:

forming an image from the acquired light;

reflecting the pencil beam before the acquiring;

determining an actual position of a particular portion of the acquired light in the image relative to a desired position of the particular portion of the acquired light; and

altering the reflecting to reduce a separation of the actual position and the desired position of the particular portion of the acquired light.

7. The method of claim 1 wherein the acquiring comprises acquiring light scattered by the eye only at approximately 90° relative to a direction of propagation of the pencil beam.

8. The method of claim 1 further comprising:

transmitting a fan beam of light into the subject's eye;

acquiring light from the fan beam scattered by the subject's eye;

forming an image of the eye from the acquired fan beam light scattered by the subject's eye; and

superimposing an ellipse on the image approximating a size and location of an iris of the eye in the image.

9. The method of claim 8 wherein the superimposing is done automatically by a computer, and is formed by the computer through analysis by the computer of light intensities in the image.

10. A diagnostic light scattering method comprising:

transmitting a pencil beam of light into a subject's eye;

acquiring light from the pencil beam scattered by the subject's eye; and

analyzing the acquired scattered light to determine a location of a reference point corresponding to an interface of a portion of the eye;

the method comprising quasi-elastic light scattering and being performed using a device, the method further comprising performing fluorescent ligand scanning using the same device, the performing fluorescent ligand scanning comprising:

illuminating the subject's eye;

measuring first data of fluorescence of the eye before introducing an imaging agent into the eye;

introducing the imaging agent into the eye;

measuring second data of fluorescence of the eye after introducing the imaging agent into the eye; and

comparing the first and second data.