Granted Patent
B2
US 7,842,468 · App. 12/254,320 · Granted Nov 30, 2010
Methods for diagnosing and treating neuroendocrine cancer
Assignee:
Trustees of Dartmouth College
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Abstract
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed.
Claims (1)
1. A method for diagnosing small cell lung cancer (SCLC) or breast cancer comprising isolating a lung tissue sample or breast tissue sample from a subject, detecting the presence of at least one NMDA glutamate receptor protein in the lung tissue sample or breast tissue sample, and diagnosing the subject as having SCLC or breast cancer, respectively, when the presence of the at least one NMDA glutamate receptor protein is detected.
Assignments (3)
CONFIRMATORY LICENSE
Recorded May 11, 2017
From: DARTMOUTH COLLEGE
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 042444/0327 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE'S STATE PREVIOUSLY RECORDED ON REEL 021893 FRAME 0022. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNEE RESIDES IN THE STATE OF NEW HAMPSHIRE, NOT NEW JERSEY.
Recorded Oct 22, 2010
From: NORTH, WILLIAM G.
To: TRUSTEES OF DARMOUTH COLLEGE
Reel/Frame 025208/0987 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 26, 2008
From: NORTH, WILLIAM G.
To: TRUSTEES OF DARTMOUTH COLLEGE
Reel/Frame 021893/0022 →
Continuity (4)
Continuation In Part
PCTUS200601466000
· Apr 19, 2006
Provisional Application
6067282900
· Apr 19, 2005