Amyloid and amyloid-like structures
View Patent ↗The present invention describes a methods, uses, compositions such as adhesive, sealants and coatings, scaffold material, composite material, all comprising amyloid-like materials such as fibrils, in particular those made from fruit or vegetable proteins. The amyloid-like materials impart good mechanical strength to the materials in which it is employed. Inhibition of amyloid formation is also described.
1. A synthetic adhesive composition comprising:
an amyloid-like component having a cross beta sheet quaternary structure, the amyloid-like component comprising at least one peptide or protein having an adhesion group;
wherein the peptide or protein is selected from the group consisting of fruit protein, fruit peptide, vegetable peptide, vegetable protein, banana peptide, banana protein, potato peptide and potato protein.
2. A composition according to claim 1 wherein the amyloid-like component is formed from an amyloid precursor peptide or protein.
3. A composition according to claim 1 wherein the amyloid-like component is in the form of fibrils.
4. A sealant composition comprising:
an amyloid-like component having a cross beta sheet quaternary structure, the amyloid-like component comprising at least one peptide or protein; and
a curable component;
and in which said amyloid-like component imparts mechanical strength to the cure product of the curable component.
5. A synthetic adhesive composition comprising a curable component; and
an amyloid-like component having a cross beta sheet quaternary structure, the amyloid-like component comprising at least one peptide or protein having an adhesion group.
6. A composition according to claim 5 further comprising a cure component for curing the curable component.
7. A sealant composition according to claim 4 further comprising a cure component for curing the curable component.