Methods for diagnosing endometriosis
View Patent ↗Provided herein is a method for diagnosing and monitoring endometriosis in a subject by measuring levels of the β-subunit of fibrinogen.
1. A kit for diagnosing endometriosis in a subject, comprising an antibody capable of specifically detecting fibrinogen β-subunit and instructions for
(a) providing a sample isolated from the subject; and
(b) measuring the level of fibrinogen β-subunit in the sample, wherein a level of fibrinogen β-subunit lower than the level of a control is indicative of endometriosis.
2. The kit of claim 1 , further comprising a positive control.
3. The kit of claim 2 , wherein the positive control is a β-subunit composition having a known concentration of the β-subunit.
4. The kit of claim 1 , further comprising a buffer.
5. The kit of claim 4 , wherein the buffer is a salt.
6. The kit of claim 1 , wherein the antibody is labeled.
7. The kit of claim 6 , further comprising a first agent capable of inducing the label to generate a signal.
8. The kit of claim 7 , further comprising a second agent capable of stopping the label from generating a signal.
9. The kit of claim 1 , further comprising one or more containers.