IP Library Granted Patent US 7,911,621
Granted Patent B2
US 7,911,621 · App. 12/016,303 · Granted Mar 22, 2011

Apparatus and method for controlling ranging depth in optical frequency domain imaging

Assignee: The General Hospital Corporation
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,911,621
App. No.
12/016,303
Granted
Mar 22, 2011
Kind
B2
Abstract

Exemplary embodiments of an apparatus are provided. For example, the exemplary apparatus can include at least one first arrangement providing at least one first electro-magnetic radiation to a sample, at least one second electro-magnetic radiation to a first reference and at least one third electro-magnetic radiation to a second reference. A frequency of radiation provided by the first arrangement generally varies over time. The exemplary apparatus may also include at least one second arrangement which is configured to detect a first interference between at least one fourth electro-magnetic radiation associated with the first electro-magnetic radiation and at least one fifth electro-magnetic radiation associated with the second radiation. The second arrangement is also configured to detect a second interference between at least one sixth electro-magnetic radiation associated with the first electro-magnetic radiation and at least one seventh electro-magnetic radiation associated with the third radiation.

Claims (13)

1. An apparatus comprising:

a first arrangement providing a first electro-magnetic radiation to a sample, a second electro-magnetic radiation to a first reference path and a third electro-magnetic radiation to a second reference path, wherein a frequency of radiation provided by the first arrangement varies over time; and

a second arrangement configured to simultaneously detect:

(i) all depth points for a first interference which is between a fourth electro-magnetic radiation associated with the first electro-magnetic radiation and a fifth electro-magnetic radiation associated with the second radiation, and

(ii) all depth points for a second interference which is between the fourth electro-magnetic radiation and a sixth electro-magnetic radiation associated with the third radiation.

2. The apparatus according to claim 1 , wherein an optical path length of the first reference path is substantially different from an optical path length of the second reference path.

3. The apparatus according to claim 2 , wherein the difference between the optical path length of the first reference and the optical path length of the second reference path is more than 500 μm.

4. The apparatus according to claim 1 , wherein the first reference path has a further arrangement to shift a frequency of the second electro-magnetic radiation.

5. The apparatus according to claim 4 , wherein the second reference path has an additional arrangement to shift a frequency of the third electro-magnetic radiation.

6. The apparatus according to claim 4 , wherein a magnitude of the shift of the frequency of the second electro-magnetic radiation is different from a magnitude of the shift of the frequency of the third electro-magnetic radiation.

7. The apparatus according to claim 1 , wherein the first electro-magnetic radiation has a spectrum whose mean frequency changes substantially continuously over time at a tuning speed that is greater than 100 Tera Hertz per millisecond.

8. The apparatus according to claim 1 , wherein the fourth radiation is provided from a particular location of the sample.

9. The apparatus according to claim 1 , further comprising a third arrangement which is configured to generate a depth profile for at least one portion of the sample based on the first and second interferences.

Assignments (3)
CONFIRMATORY LICENSE Recorded Apr 14, 2010
From: MASSACHUSETTS GENERAL HOSPITAL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024231/0183 →
CONFIRMATORY LICENSE Recorded Mar 15, 2010
From: GENERAL HOSPITAL CORPORATION DBA MASS
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024081/0007 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 18, 2008
From: NEZAM, REZA MOTAGHIAN; TEARNEY, GUILLERMO J.; BOUMA, BRETT EUGENE
To: THE GENERAL HOSPITAL CORPORATION
Reel/Frame 020382/0624 →
Continuity (2)
Provisional Application 60885652 · Jan 19, 2007
Related Publication 20080297806A1 · Dec 4, 2008