Dermal application system for aminolaevulinic acid
The invention relates to a dermal for aminolaevulinic acid, wherein a self-adhesive matrix system is used containing crystalline aminolaevulinic acids.
1. A dermal application system, which is a self-adhesive matrix system, consisting of aminolaevulinic acid (ALA) hydrochloride crystals suspended in a polymer matrix, wherein the polymer matrix consists of polymers from the group consisting of acrylates, and polyisobutylene, wherein a substantial amount of the ALA hydrochloride crystals have a mean diameter of 20 μm to 200 μm.
2. Application system according to claim 1 , characterized in that the ALA hydrochloride crystals have a mean diameter of 30 μm to 190 μm.
3. Application system according to claim 2 , characterized in that the ALA hydrochloride crystals have a mean diameter of 90 μm to 160 μm.
4. Application system according to claim 1 , characterized in that the ALA hydrochloride is present in a concentration of 1 to 50 wt. % relative to the polymer matrix.
5. Application system according to claim 1 , characterized in that it releases at least 30% of the ALA hydrochloride within 30 minutes.