IP Library Granted Patent US 7,964,587
Granted Patent B2
US 7,964,587 · App. 11/159,917 · Granted Jun 21, 2011

Tocopherol and tocotrienol aerosols

Assignee: Children's Hospital & Research Center at Oakland
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Quick Facts
Patent No.
US 7,964,587
App. No.
11/159,917
Granted
Jun 21, 2011
Kind
B2
Abstract

Anti-inflammatory compositions include medicaments comprising predetermined amounts of a phytyl substituted chromanol and a prostaglandin E 2 inhibitor, wherein: said medicament is in unit dosage form suitable for pharmaceutical administration; said phytyl substituted chromanol is a gamma-tocopherol, delta-tocopherol, gamma-tocotrienol or delta-tocotrienol; said PGE 2 inhibitor is a non-steroidal anti-inflammatory drug or an omega-3 fatty acid, such as docosahexaenoic acid and eicosapentaenoic acid.

Claims (6)

1. A method of inhibiting proliferation of human prostate epithelial cancer cells or human lung epithelial cancer cells in a person, the method comprising administering to the person in unit dosage form a medicament consisting of 150 mg gamma-tocopherol, 150 mg gamma-tocotrienol, 50 mg acetaminophen, and one or more carrier, vehicle or excipient suitable for use in pharmaceutical compositions.

2. The method of claim 1 wherein the cells are the human prostate epithelial cancer cells and the medicament is administered orally.

3. The method of claim 1 wherein the cells are the human lung epithelial cancer cells and the medicament is administered as an inhalant.

4. A method of inhibiting proliferation of human prostate epithelial cancer cells or human lung epithelial cancer cells in a person, the method comprising administering to the person in unit dosage form a medicament consisting of 150 mg gamma-tocopherol, 150 mg gamma-tocotrienol, 50 mg aspirin, and one or more carrier, vehicle or excipient suitable for use in pharmaceutical compositions.

5. The method of claim 4 wherein the cells are the human prostate epithelial cancer cells and the medicament is administered orally.

6. The method of claim 4 wherein the cells are the human lung epithelial cancer cells and the medicament is administered as an inhalant.

Assignments (2)
CONFIRMATORY LICENSE Recorded Feb 26, 2014
From: CHILDREN'S HOSPITAL & RES CTR AT OAKLAND
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 032335/0413 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2005
From: AMES, BRUCE N.; JIANG, QING
To: CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND
Reel/Frame 016727/0150 →
Continuity (2)
Continuation 10301211 · Nov 21, 2002
Related Publication 20050239876A1 · Oct 27, 2005