Bag proteins and nucleic acid molecules encoding them
View Patent ↗The present invention provides a family of BAG-1 related proteins from humans (BAG-1L, BAG-1, BAG-2, BAG-3, BAG-4 and BAG-5), the invertebrate C. elegans (BAG-1, BAG-2) and the fission yeast S. pombe (BAG-1A, BAG-1B) and the nucleic acid molecules that encode them.
1. A substantially purified nucleic acid molecule having the nucleotide sequence of SEQ ID NO: 5.
2. A substantially purified nucleic acid molecule having a nucleotide sequence of at least 25 contiguous nucleotides of the nucleotide sequence of SEQ ID NO: 5.
3. A substantially purified nucleic acid molecule having a nucleotide sequence fully complementary to at least 25 nucleotides of the nucleotide sequence of SEQ ID NO:5.
4. The nucleic acid of claim 3 having a nucleotide sequence fully complementary to a nucleotide sequence that encodes a functionally active BAG family protein comprising the amino acid sequence of SEQ ID NO:6.
5. The nucleic acid of claim 4 comprising the nucleotide sequence of SEQ ID NO:5.
6. A composition comprising a nucleic acid molecule of claim 1 .