IP Library Granted Patent US 7,989,495
Granted Patent B2
US 7,989,495 · App. 10/505,244 · Granted Aug 2, 2011

Compositions and methods for inhibiting NF-κB mediated tumorigenicity and adhesion dependent survival of cancer cells

Assignee: University of Utah Research Foundation
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Quick Facts
Patent No.
US 7,989,495
App. No.
10/505,244
Granted
Aug 2, 2011
Kind
B2
Abstract

Disclosed are compositions and methods for inhibiting NF-κB mediated cellular proliferation and metastasis.

Claims (8)

1. A method for inhibiting reseeding of HT-29 colon cancer cells during or after surgical resection of a tumor: comprising administering to a subject within 10 days of the resection, a compound having the structure

2. The method of claim 1 , wherein the compound is administered prior to the resection.

3. The method of claim 1 , wherein the compound is administered after the resection.

4. The method of claim 1 , wherein the compound is administered within 5 days of the resection.

5. The method of claim 1 , wherein the compound is administered within 1 day of the resection.

6. The method of claim 1 , wherein the compound is administered within 10 hours of the resection.

7. The method of claim 1 , wherein the compound is administered within 1 hour of the resection.

8. The method of claim 1 , wherein the compound is administered within 0.5 hours of the resection.

Assignments (3)
CONFIRMATORY LICENSE Recorded Sep 5, 2017
From: UNIVERSITY OF UTAH
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 043750/0724 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 17, 2005
From: UTAH, UNIVERSITY OF
To: UNIVERSITY OF UTAH RESEARCH FOUNDATION
Reel/Frame 016249/0044 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 29, 2004
From: KUWADA, SCOTT K.
To: UTAH, UNIVERSITY OF
Reel/Frame 015506/0227 →
Continuity (2)
Provisional Application 60358853 · Feb 21, 2002
Related Publication 20050124590A1 · Jun 9, 2005