IP Library Granted Patent US 8,008,356
Granted Patent B2
US 8,008,356 · App. 10/590,668 · Granted Aug 30, 2011

Polyaphron dispersions containing a complex internal phase

Assignee: Drug Delivery Solutions Limited
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Quick Facts
Patent No.
US 8,008,356
App. No.
10/590,668
Granted
Aug 30, 2011
Kind
B2
Abstract

A polyaphron dispersion comprising an external phase and polyaphrons having an internal phase, the internal phase comprising (i) a first phase which is liquid and (ii) a second phase which is liquid or gaseous.

Claims (38)

1. A polyaphron dispersion comprising:

from about 5% to about 30% by weight based on the total weight of the polyaphron dispersion of an external phase; and

from about 70% to about 95% by weight based on the total weight of the polyaphron dispersion of polyaphrons having an internal phase, the internal phase comprising:

(i) a first phase which is liquid, and

(ii) a second phase which is liquid or gaseous;

wherein when the internal phase comprises at least two liquid phases, each of the liquid phases is a liquid at room temperature.

2. The polyaphron dispersion according to claim 1 , wherein the internal phase comprises at least two liquid phases.

3. The polyaphron dispersion according to claim 1 , wherein the internal phase comprises an aqueous phase and a non-aqueous phase.

4. The polyaphron dispersion according to claim 3 , wherein the internal phase comprises a single aqueous phase and a single non-aqueous phase.

5. The polyaphron dispersion according to claim 1 , wherein the internal phase comprises an emulsion.

6. The polyaphron dispersion according to claim 1 wherein the internal phase comprises polyaphrons.

7. The polyaphron dispersion according to claim 1 , wherein the internal phase additionally comprises a solid phase.

8. The polyaphron dispersion according to claim 1 , wherein the internal phase comprises at least 60 wt. % of an aqueous phase.

9. The polyaphron dispersion according to claim 1 , wherein a component of the external phase is capable of reacting with a component of the internal phase upon the polyaphrons being disrupted or destroyed.

10. A process for preparing a polyaphron dispersion as defined in claim 1 , which comprises:

a. forming the internal phase; and

b. forming a polyaphron dispersion comprising an external phase and the internal phase prepared in step a.

11. The polyaphron dispersion according to claim 1 , wherein the external phase is aqueous.

12. The polyaphron dispersion according to claim 1 , wherein the second phase is gaseous and the internal phase additionally comprises a solid phase.

13. A polyaphron dispersion comprising:

from about 5% to about 30% by weight based on the total weight of the polyaphron dispersion of an external phase; and

from about 70% to about 95% by weight based on the total weight of the polyaphron dispersion of polyaphrons having an internal phase, the internal phase comprising:

(i) a first phase which is liquid, and

(ii) a second phase which is liquid or gaseous;

wherein when the internal phase comprises at least two liquid phases, each of the liquid phases is a liquid at room temperature,

wherein the internal phase comprises polyaphrons.

14. The polyaphron dispersion according to claim 13 , wherein the external phase is aqueous.

15. The polyaphron dispersion according to claim 13 , wherein the internal phase comprises at least two liquid phases.

16. The polyaphron dispersion according to claim 13 , wherein the internal phase comprises an aqueous phase and a non-aqueous phase.

17. A polyaphron dispersion comprising:

from about 5% to about 30% by weight based on the total weight of the polyaphron dispersion of an external phase; and

from about 70% to about 95% by weight based on the total weight of the polyaphron dispersion of polyaphrons having an internal phase, the internal phase comprising:

(i) a first phase which is liquid, and

(ii) a second phase which is liquid or gaseous;

wherein when the internal phase comprises at least two liquid phases, each of the liquid phases is a liquid at room temperature,

wherein the internal phase comprises at least 60 wt. % of an aqueous phase.

18. The polyaphron dispersion according to claim 17 , wherein the external phase is aqueous.

19. The polyaphron dispersion according to claim 17 , wherein the internal phase comprises at least two liquid phases.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2007
From: CHILDS, ANDREW; WHEELER, DEREK
To: DRUG DELIVERY SOLUTIONS LIMITED
Reel/Frame 019053/0583 →
Priority Claims (1)
GB 0404403.8 · Feb 27, 2004 · national
Continuity (1)
Related Publication 20070190088A1 · Aug 16, 2007