IP Library › Granted Patent US 8,034,337
Granted Patent B2
US 8,034,337 · App. 12/455,458 · Granted Oct 11, 2011

Interleukin-1α antibodies

Assignee: Xbiotech, Inc.
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Quick Facts
Patent No.
US 8,034,337
App. No.
12/455,458
Granted
Oct 11, 2011
Kind
B2
Abstract

Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the complement system though C1q binding and binding to several different Fc receptors.

Claims (1)

1. A purified human IgG1 monoclonal antibody that specifically binds to human interleukin-1 alpha, the monoclonal antibody comprising a heavy chain covalently joined to a light chain, wherein the heavy chain comprises the amino acid sequence of SEQ ID NO: 9 and the light chain comprises the amino acid sequence of SEQ ID NO:11.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2020
From: XBIOTECH INC.
To: JANSSEN BIOTECH, INC.
Reel/Frame 051769/0927 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2009
From: SIMARD, JOHN
To: XBIOTECH, INC.
Reel/Frame 023091/0933 →
Continuity (4)
Provisional Application 61057586 · May 30, 2008
Provisional Application 61121391 · Dec 10, 2008
Provisional Application 61178350 · May 14, 2009
Related Publication 20090298096A1 · Dec 3, 2009