IP Library Granted Patent US 8,097,652
Granted Patent B2
US 8,097,652 · App. 12/517,431 · Granted Jan 17, 2012

AMPA receptor potentiators

Assignee: Eli Lilly and Company
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Quick Facts
Patent No.
US 8,097,652
App. No.
12/517,431
Granted
Jan 17, 2012
Kind
B2
Abstract

The present invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of conditions associated with glutamate hypofunction, such as psychiatric and neurological disorders.

Claims (9)

1. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical formulation comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof in combination with a pharmaceutically acceptable carrier, diluent or excipient.

3. The compound of claim 1 for use as a pharmaceutical.

4. A method of potentiating glutamate receptor function in a mammal comprising administering to a mammal in need of such treatment an effective amount of a compound of claim 1 .

5. A method of treating Parkinson's disease comprising administering to a mammal in need of such treatment an effective amount of a compound of claim 1 .

6. A method of treating depression comprising administering to a mammal in need of such treatment an effective amount of a compound of claim 1 .

7. A method of treating schizophrenia comprising administering to a mammal in need of such treatment an effective amount of a compound of claim 1 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 8, 2009
From: DOMINGUEZ-MANZANARES, ESTEBAN
To: ELI LILLY AND COMPANY
Reel/Frame 022926/0443 →
Priority Claims (1)
EP 06380319 · Dec 11, 2006 · regional
Continuity (2)
Provisional Application 60888562 · Feb 7, 2007
Related Publication 20100010090A1 · Jan 14, 2010