IP Library › Granted Patent US 8,101,775
Granted Patent B2
US 8,101,775 · App. 12/520,145 · Granted Jan 24, 2012

Indole derivatives as S1P1 Receptor

Assignee: Glaxo Group Limited
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Quick Facts
Patent No.
US 8,101,775
App. No.
12/520,145
Granted
Jan 24, 2012
Kind
B2
Abstract

The invention relates to compounds of formula (I) wherein one of R 5 and R 6 is hydrogen or R 2 and the other is (a) pharmaceutical compositions containing them and their use in the treatment of conditions or disorders which are mediated via the S1P1 receptor.

Claims (5)

1. 4-[4-(5-{5-chloro-6-[(1-methylethyl)oxy]-3-pyridinyl}-1,2,4-oxadiazol-3-yl)-1H-indol-1-yl]butanoic acid;

and pharmaceutically acceptable salts thereof.

2. A pharmaceutical composition comprising a compound of claim 1 and one or more pharmaceutically-acceptable excipients.

3. 4-[4-(5- {5-chloro-6-[(1-methylethyl)oxy]-3-pyridinyl}-1,2,4-oxadiazol-3-yl)-1H-indol-1-yl]butanoic acid hydrochloride.

4. A pharmaceutical composition comprising a compound of claim 3 and one or more pharmaceutically-acceptable excipients.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 18, 2011
From: AHMED, MAHMOOD; RIVERS, DEAN ANDREW; MYATT, JAMES; NORTON, DAVID
To: GLAXO GROUP LIMITED
Reel/Frame 025978/0834 →
Priority Claims (2)
GB 0625647.3 · Dec 21, 2006 · national
GB 0707615.1 · Apr 19, 2007 · national
Continuity (1)
Related Publication 20100113796A1 · May 6, 2010