Rapid cryo-heating devices and their applications
This invention discloses cryo-heating devices and methods for cooling and heating objects in a very rapid timescale, from femtosecond to subsecond. The cryo-heating device comprising of an up-converting electromagnetic energy medium and an electromagnetic source that is further supported by another radiation source selected from the group of sonic, magnetic, electric, electroluminescent, up-converted luminescence, pressure and thermal. The medium in the cryo-heating phototreatment device is cooling or heating objects by up-conversion of electromagnetic energy and by conversion of electromagnetic energy, respectively. Both, cooling and heating of objects are achieved by electromagnetic radiation at different wavelengths, or at the same wavelength when objects are also absorbing electromagnetic radiation. The invention also proposes a further enhancement of cooling and heating of objects by the use of surface plasmon resonance conducting nanostructures embedded into the medium. The proposed devices and methods of very rapid cooling and heating can be applied in biomedical technologies and health care. The invention also includes applications of the disclosed herein method to up-conversion energy cooling of electronic components and photon detector devices.
1. A method of rapid repeated cooling and heating of molecules by up-converting energy medium comprising steps of: providing a molecule to be cooled and heated; providing an up-converting energy medium, wherein the up-converting energy medium is capable of being cooled by electromagnetic radiation at wavelength 1 and heated by electromagnetic radiation at wavelength 2 ; providing an electromagnetic source capable of radiating electromagnetic radiation at wavelength 1 and at wavelength 2 ; contacting the molecule with the up-converting energy medium; irradiating the up-converting energy medium with electromagnetic radiation at wavelength 1 to cool the molecule by the up-converting energy medium; irradiating the up-converting energy medium with electromagnetic radiation at wavelength 2 to heat the molecule by the up-converting energy medium; irradiating the up-converting energy medium with electromagnetic radiation at wavelength 1 to cool the molecule by the up-converting energy medium; and irradiating the up-converting energy medium with electromagnetic radiation at wavelength 2 to heat the molecule by the up-converting energy medium.
2. The method of claim 1 , wherein said the molecule is selected from the group of: a genetic material, biomolecule, cell, tissue, skin, joint, nerve, meridian, body fluid, plant, food, microbe, or fungi.
3. The method of claim 1 , wherein said electromagnetic source is radiating electromagnetic radiation at a wavelength range from ultraviolet to microwave.
4. The method of claim 1 , wherein said electromagnetic source is a continuous radiation source or a pulsed radiation source.