Chemical compositions and methods of making them
Bimetal chelates are prepared from a solution formed by adding to a solvent one or more polyfunctional acids with basic salts of two or more coordination elements listed in Groups IIIA to VIIIA, Groups IB to IIIB, of periods 4 and 5 and aluminum in Group IIIB, period 3 of The Periodic Table of the Elements and recovering the chelate. Such chelates can be used to formulate useful products.
1. A method of forming a bimetal chelate, the method comprising
forming a solution by adding to a solvent (i) a polyfunctional carboxylic acid having two or more acid groups and (ii) basic salts of two or more coordination elements selected from one or more of copper, silver, gold, aluminum, scandium, titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper, zinc, gallium, yttrium, zirconium, niobium, molybdenum, technetium, ruthenium, rhodium, palladium, silver, cadmium, and indium; and
recovering a bimetal chelate that includes the two or more coordination elements joined to a central unit derived from the polyfunctional carboxylic acid.
2. A method as in claim 1 wherein forming a solution comprises adding to a solvent one or more polyfunctional carboxylic acids having two or more acid groups selected from maleic acid, fumaric acid, citraconic acid, itaconic acid, glutaconic acid, phthalic acid, isophthalic acid, terephthalic acid, cyclohexane dicarboxylic acid, succinic acid, adipic acid, sebacic acid, azealic acid, malonic acid, dodecanedioic acid, 1,18-octadecanedioic acid and alkenyl succinic acids.
3. A method as in claim 1 wherein forming a solution comprises adding malonic acid to a solvent.
4. A method as in claim 1 wherein forming a solution comprises adding at least one basic salt that provides Cu +2 ions in the solution.
5. A method as in claim 1 wherein forming a solution comprises adding cupric carbonate to a solvent.
6. A method as in claim 1 wherein forming a solution comprises adding at least one basic salt that provides Zn +2 ions in the solution.
7. A method as in claim 1 wherein forming a solution comprises adding zinc carbonate to a solvent.
8. A method as in claim 1 wherein forming a solution by adding to a solvent (i) a polyfunctional carboxylic acid having two or more acid groups and (ii) basic salts of two or more coordination elements results in a molar ratio of polyfunctional acid to ions of the two or more coordination elements of about 3:2.
9. A method comprising:
formulating a product by combining a pharmaceutically or dermatologically acceptable carrier with a chelate formed by a polyfunctional carboxylic acid having two or more acid groups with basic salts of two or more coordination elements selected from one or more of copper, silver, gold, aluminum, scandium, titanium, vanadium, chromium, manganese, iron, cobalt, nickel, copper, zinc, gallium, yttrium, zirconium, niobium, molybdenum, technetium, ruthenium, rhodium, palladium, silver, cadmium, and indium, wherein the chelate includes two or more coordination elements are joined to a central unit derived from the polyfunctional carboxylic acid.
10. A method as in claim 9 further comprising including in the product one or more members selected from the group consisting of antimicrobials, moisturizers, hydration agents, penetration agents, preservatives, emulsifiers, natural oils, synthetic oils, surfactants, detergents, gelling agents, emollients, antioxidants, fragrances, fillers, thickeners, waxes, odor absorbers, dyestuffs, coloring agents, powders, viscosity-controlling agents, anesthetics, anti-itch actives, botanical extracts, conditioning agents, darkening agents, lightening agents, glitter, humectants, mica, minerals, polyphenols, silicones, sunblocks, vitamins, and phytomedicinals.
11. A method as in claim 9 wherein the product comprises the chelate in an amount from about 0.001 to about 5% by weight of the total product.