Skin treatment composition
View Patent ↗A skin treatment composition of the present invention is an external composition for skin comprising an alkylene oxide derivative expressed by Formula (I): R 1 O-[(AO) m (EO) n ]—R 2 (I) wherein AO is an oxyalkylene group of C 3 or C 4 ; EO is an oxyethylene group; m and n are 1≦m≦70 and 1≦n≦70 respectively, wherein EO is 20˜80% by weight with respect to a total of AO and EO; each of R 1 and R 2 is a hydrogen or a hydrocarbon group having C 1-4 . The alkylene oxide derivative (I) has a moisturizing effect, a rough skin improving effect, a stickiness improving effect, and a transdermal absorption promoting effect. When a refreshing agent is used together therewith in the composition of the present invention, the refreshing effect lasts for a long time and it is excellent in feeling of use without skin stimulation.
1. A cosmetic method for skin or hair, comprising:
applying externally to said skin or hair a composition comprising an alkylene oxide derivative expressed by Formula (I):
R 1 O-[(AO) m (EO) n ]—R 2 (I)
wherein AO is an oxyalkylene group having a carbon number of 3 or 4; EO is an oxyethylene group; m and n are average addition numbers of said AO and EO, respectively, which are 1≦m≦70 and 1≦n≦70,
wherein said EO is 20-80% by weight with respect to a total of said AO and EO;
wherein said AO and EO are added to each other in block or random form;
wherein R 1 and R 2 are either identical to or different from each other, and
wherein said R 1 and said R 2 are alkyl groups having a carbon number of 1-4.
2. The method of claim 1 , wherein said alkylene oxide derivative is 0.01-80% by weight of said composition.
3. The method of claim 1 , wherein said composition further comprises a water-soluble medicament.
4. The method of claim 1 , wherein said composition further comprises a humectant.
5. The method of claim 4 , wherein said humectant is xylitol or glycerin.
6. The method of claim 1 , wherein said composition further comprises a skin whitening agent.
7. The method of claim 6 , wherein said skin whitening agent is selected from the group consisting of arbutin, ascorbyl glucoside, magnesium ascorbyl phosphate and ethyl ascorbic acid.
8. The method of claim 1 , wherein said composition further comprises a refreshing agent.
9. The method of claim 8 , wherein said refreshing agent is menthol or camphor.
10. The method of claim 1 , wherein said R 1 is methyl or ethyl and said R 2 is methyl.
11. The method of claim 1 , wherein said AO and EO are added to each other in random form.
12. The method of claim 1 , wherein said alkylene oxide is a moisturizing agent, a rough skin or hair improving agent, a stickiness improving agent, or a transdermal absorption improving agent.
13. A method for improving transdermal absorption of a water-soluble medicament comprising:
adding to an external composition containing the water-soluble medicament an effective amount of an alkylene oxide derivative expressed by Formula (I):
R 1 O-[(AO) m (EO) n ]—R 2 (I)
wherein AO is an oxyalkylene group having a carbon number of 3 or 4; EO is an oxyethylene group; m and n are average addition numbers of said AO and EO, respectively, which are 1≦m≦70 and 1≦n.≦70,
wherein said EO is 20%-80% by weight with respect to a total of said AO and EO;
wherein said AO and EO are added to each other in block or random form;
wherein R 1 and R 2 are either identical to or different from each other, and
wherein said R 1 and said R 2 are alkyl groups having a carbon number of 1-4.
14. The method of claim 13 , wherein said external composition is a cream, a lotion, a foundation, a lipstick, a gel, a deodorant stick, or a hair tonic.
15. The method of claim 13 , wherein said R 1 is methyl or ethyl and said R 2 is methyl.
16. The method of claim 13 , wherein said AO and DO are added to each other in random form.
17. The method of claim 13 , wherein said water-soluble medicament is a humectant.
18. The method of claim 17 , wherein said humectant is xylitol or glycerin.
19. The method of claim 13 , wherein said water-soluble medicament is a skin whitening agent.
20. The method of claim 19 , wherein said skin whitening agent is selected from the group consisting of arbutin, ascorbyl glucoside, magnesium ascorbyl phosphate and ethyl ascorbic acid.
21. A method for improving a stickiness of an external composition for skin or hair, comprising:
adding to said external composition an effective amount of an alkylene oxide derivative expressed by Formula (I):
R 1 O-[(AO) m (EO) n ]—R 2 (I)
wherein AO is an oxyalkylene group having a carbon number of 3 or 4; EO is an oxyethylene group; m and n are average addition numbers of said AO and EO, respectively, which are 1≦m≦70 and 1≦n.≦70,
wherein said EU is 20-80% by weight with respect to a total of said AO and EO;
wherein said AO and O are added to each other in block or random form;
wherein R 1 and R 2 are either identical to or different from each other, and
wherein said R 1 and said R 2 are alkyl groups having a carbon number of 1-4.
22. The method of claim 21 , wherein said external composition further comprises a humectant.
23. The method of claim 21 , wherein said R 1 is methyl or ethyl and said R 2 is methyl.
24. The method of claim 21 , wherein said AO and EO are added to each other in random form.
25. A method for moisturizing human skin comprising: applying an external composition on human skin or hair, the external composition comprising: an alkylene oxide derivative expressed by Formula (I):
R 1 O-[(AO) m (EO) n ]—R 2 (I)
wherein AO is an oxyalkylene group having a carbon number of 3 or 4; EO is an oxyethylene group; m and n are average addition numbers of said AO and EO, respectively, which are 1≦m≦70 and 1≦n≦70,
wherein said EO is 20-80% by weight with respect to a total of said AO and EO;
wherein said AO and BO are added to each other in block or random form;
wherein R 1 and R 2 are either identical to or different from each other, and
wherein said R 1 and said R 2 are alkyl groups having a carbon number of 1-4.
26. The method of claim 25 , wherein said R 1 is methyl or ethyl and said R 2 is methyl.
27. The method of claim 25 , wherein said AO and BO are added to each other in random form.
28. A method for improving human rough skin or hair, comprising applying an external composition on human skin or hair, the external composition comprising: an alkylene oxide derivative expressed by Formula (I):
R 1 O-[(AO) m (EO) n ]—R 2 (I)
wherein AO is an oxyalkylene group having a carbon number of 3 or 4; EO is an oxyethylene group; m and n are average addition numbers of said AO and EO, respectively, which are 1≦m≦70 and 1≦n≦70,
wherein said EO is 20-80% by weight with respect to a total of said AO and EO;
wherein said AO and EO are added to each other in block or random form;
wherein R 1 and R 2 are either identical to or different from each other, and
wherein said R 1 and said R 2 are alkyl groups having a carbon number of 1-4.
29. The method of claim 28 , wherein said R 1 is methyl or ethyl and said R 2 is methyl.
30. The method of claim 28 , wherein said AO and EO are added to each other in random form.