Nutritional supplement for use under physiologically stressful conditions
In one embodiment of the present invention, a pharmaceutically-acceptable single-dosage formulation consists essentially of about 300 mg of vitamin C; about 1200 IUs of vitamin D3; about 125 IUs of vitamin E; about 25 mg of vitamin B1; about 3.4 mg of vitamin B2; about 35 mg of niacin; about 35 mg of vitamin B6; about 1.25 mg of folate; about 70 mcg of vitamin B12; about 5 mg of pantothenic acid; about 300 mcg of biotin; about 50 mg of calcium; about 35 mg of magnesium; about 35 mg of zinc; about 1 mg of copper; about 125 mcg of selenium; about 150 mcg of chromium; about 25 mg of alpha lipoic acid; about 35 mg of co-enzyme Q-10; about 2 mg of lutein; about 500 mcg of lycopene; about 5 mg of pepper extract; and at least one or more excipients.
1. A pharmaceutically-acceptable single-dosage formulation, consisting essentially of:
between about 150 mg to about 450 mg of vitamin C;
between about 600 IUs to about 1800 IUs of vitamin D3;
between about 75 IUs to about 150 IUs of vitamin E;
between about 15 mg to about 35 mg of vitamin B1;
between about 1.7 mg to about 5.1 mg of vitamin B2;
between about 20 mg to about 50 mg of niacin;
between about 20 mg to about 50 mg of vitamin B6;
between about 0.5 mg to about 2.5 mg of folate;
between about 35 mcg to about 105 mcg of vitamin B12;
between about 2.5 mg to about 7.5 mg of pantothenic acid;
between about 150 mcg to about 450 mcg of biotin;
between about 50 mg to about 100 mg of calcium;
between about 15 mg to about 55 mg of magnesium;
between about 15 mg to about 55 mg of zinc;
between about 0.5 to about 1.5 mg of copper;
between about 75 mcg to about 175 mcg of selenium;
between about 75 mcg to about 225 mcg of chromium;
between about 10 mg to about 40 mg of alpha lipoic acid;
between about 20 mg to about 50 mg of co-enzyme Q-10;
between about 1 mg to about 3 mg of lutein;
between about 250 mcg to about 750 mcg of lycopene;
between about 2.5 mg to about 7.5 mg of pepper extract; and
at least one or more excipients.
2. The pharmaceutically-acceptable single-dosage formulation of claim 1 , wherein the formulation consists essentially of:
about 300 mg of vitamin C;
about 1200 IUs of vitamin D3;
about 125 IUs of vitamin E;
about 25 mg of vitamin B1;
about 3.4 mg of vitamin B2;
about 35 mg of niacin;
about 35 mg of vitamin B6;
about 1.25 mg of folate;
about 70 mcg of vitamin B12;
about 5 mg of pantothenic acid;
about 300 mcg of biotin;
about 75 mg of calcium;
about 35 mg of magnesium;
about 35 mg of zinc;
about 1 mg of copper;
about 125 mcg of selenium;
about 150 mcg of chromium;
about 25 mg of alpha lipoic acid;
about 35 mg of co-enzyme Q-10;
about 2 mg of lutein;
about 500 mcg of lycopene;
about 5 mg of pepper extract; and
at least one or more excipients.
3. The formulation of claim 1 , wherein the single-dosage formulation is administered in a form selected from the group consisting of a pill, a tablet, a caplet, a capsule, a chewable tablet, a quick dissolve tablet, an effervescent tablet, a hard gelatin capsule, and a soft gelatin capsule.
4. The formulation of claim 3 , wherein the single-dosage formulation is administered in a form with an enteric coating.
5. The formulation of claim 1 , wherein the single-dosage formulation is administered in the form of a liquid suspension.
6. The formulation of claim 1 , wherein the single-dosage formulation is administered in the form of a food product.
7. The formulation of claim 1 , wherein the excipients consist essentially of at least one of dicalcium phosphate, microcrystalline cellulose, stearic acid, croscarmellose sodium, magnesium trisillicate, magnesium stearate or hydroxypropyl methylcellulose.
8. The formulation of claim 1 , wherein the at least one or more excipients consist of:
between about 100 mg to about 300 mg of dicalcium phosphate;
between about 25 mg to about 75 mg of microcrystalline cellulose;
between about 10 mg to about 30 mg of stearic acid;
between about 10 mg to about 30 mg of croscarmellose sodium;
between about 5 mg to about 15 mg of magnesium trisillicate;
between about 5 mg to about 15 mg of magnesium stearate; and
between about 5 mg to about 15 mg of hydroxypropyl methylcellulose.
9. The formulation of claim 8 , wherein the at least one or more excipients consist of:
about 200 mg of dicalcium phosphate;
about 50 mg of microcrystalline cellulose;
about 20 mg of stearic acid;
about 20 mg of croscarmellose sodium;
about 10 mg of magnesium trisillicate;
about 10 mg of magnesium stearate; and
about 10 mg of hydroxypropyl methylcellulose.
10. A pharmaceutically-acceptable single-dosage formulation, consisting of:
between about 150 mg to about 450 mg of ascorbic acid;
between about 600 IUs to about 1800 IUs of cholecalciferol;
between about 75 IUs to about 150 IUs of d-alpha tocopherol succinate;
between about 15 mg to about 35 mg of thiamine mononitrate;
between about 1.7 mg to about 5.1 mg of riboflavin;
between about 20 mg to about 50 mg of niacinamide;
between about 20 mg to about 50 mg of pyridoxine hcl;
between about 0.5 mg to about 2.5 mg of folic acid;
between about 35 mcg to about 105 mcg of cyanocobalamin;
between about 2.5 mg to about 7.5 mg of d-calcium pantothenate;
between about 150 mcg to about 450 mcg of d-biotin;
between about 50 mg to about 100 mg of dicalcium malate;
between about 15 mg to about 55 mg of dimagnesium malate;
between about 15 mg to about 55 mg of zinc bisglycinate chelate;
between about 0.5 to about 1.5 mg of copper amino acid chelate;
between about 75 mcg to about 175 mcg of selenium amino acid chelate;
between about 75 mcg to about 225 mcg of chromium amino acid chelate;
between about 10 mg to about 40 mg of alpha lipoic acid;
between about 20 mg to about 50 mg of co-enzyme Q-10;
between about 1 mg to about 3 mg of lutein;
between about 250 mcg to about 750 mcg of lycopene;
between about 2.5 mg to about 7.5 mg of pepper extract; and
at least one or more excipients.
11. The pharmaceutically-acceptable single-dosage formulation of claim 10 , wherein the formulation consists of:
about 300 mg of ascorbic acid
about 1200 IUs of cholecalciferol;
about 125 IUs of d-alpha tocopherol succinate;
about 35 mg of thiamine mononitrate;
about 5.1 mg of riboflavin;
about 50 mg of niacinamide;
about 50 mg of pyridoxine hcl;
about 2.5 mg of folic acid;
about 105 mcg of cyanocobalamin;
about 7.5 mg of d-calcium pantothenate;
about 450 mcg of d-biotin;
about 75 mg of dicalcium malate;
about 55 mg of dimagnesium malate;
about 55 mg of zinc bisglycinate chelate;
about 1.5 mg of copper amino acid chelate;
about 175 mcg of selenium amino acid chelate;
about 225 mcg of chromium amino acid chelate;
about 40 mg of alpha lipoic acid;
about 50 mg of co-enzyme Q-10;
about 3 mg of lutein;
about 750 mcg of lycopene;
about 7.5 mg of pepper extract; and
at least one or more excipients.
12. The formulation of claim 10 , wherein the single-dosage formulation is administered in a form selected from the group consisting of a pill, a tablet, a caplet, a capsule, a chewable tablet, a quick dissolve tablet, an effervescent tablet, a hard gelatin capsule, and a soft gelatin capsule.
13. The formulation of claim 12 , wherein the single-dosage formulation is administered in a form with an enteric coating.
14. The formulation of claim 10 , wherein the single-dosage formulation is administered in the form of a liquid suspension.
15. The formulation of claim 10 , wherein the single-dosage formulation is administered in the form of a food product.
16. The formulation of claim 10 , wherein the excipients consist of at least one of dicalcium phosphate, microcrystalline cellulose, stearic acid, croscarmellose sodium, magnesium trisillicate, magnesium stearate or hydroxypropyl methylcellulose.
17. The formulation of claim 10 , wherein the at least one or more excipients consist of:
between about 100 mg to about 300 mg of dicalcium phosphate;
between about 25 mg to about 75 mg of microcrystalline cellulose;
between about 10 mg to about 30 mg of stearic acid;
between about 10 mg to about 30 mg of croscarmellose sodium;
between about 5 mg to about 15 mg of magnesium trisillicate;
between about 5 mg to about 15 mg of magnesium stearate; and
between about 5 mg to about 15 mg of hydroxypropyl methylcellulose.
18. The formulation of claim 17 , wherein the at least one or more excipients consist of:
about 200 mg of dicalcium phosphate;
about 50 mg of microcrystalline cellulose;
about 20 mg of stearic acid;
about 20 mg of croscarmellose sodium;
about 10 mg of magnesium trisillicate;
about 10 mg of magnesium stearate; and
about 10 mg of hydroxypropyl methylcellulose.
19. A pharmaceutically-acceptable single-dosage formulation, consisting of:
between about 150 mg to about 450 mg of ascorbic acid;
between about 600 IUs to about 1800 IUs of cholecalciferol;
between about 75 IUs to about 150 IUs of d-alpha tocopherol succinate;
between about 15 mg to about 35 mg of thiamine mononitrate;
between about 1.7 mg to about 5.1 mg of riboflavin;
between about 20 mg to about 50 mg of niacinamide;
between about 20 mg to about 50 mg of pyridoxine hcl;
between about 0.5 mg to about 2.5 mg of folic acid;
between about 35 mcg to about 105 mcg of cyanocobalamin;
between about 2.5 mg to about 7.5 mg of d-calcium pantothenate;
between about 150 mcg to about 450 mcg of d-biotin;
between about 50 mg to about 100 mg of dicalcium malate;
between about 15 mg to about 55 mg of dimagnesium malate;
between about 15 mg to about 55 mg of zinc bisglycinate chelate;
between about 0.5 to about 1.5 mg of copper amino acid chelate;
between about 75 mcg to about 175 mcg of selenium amino acid chelate;
between about 75 mcg to about 225 mcg of chromium amino acid chelate;
between about 10 mg to about 40 mg of alpha lipoic acid;
between about 20 mg to about 50 mg of co-enzyme Q-10;
between about 1 mg to about 3 mg of lutein;
between about 250 mcg to about 750 mcg of lycopene;
between about 2.5 mg to about 7.5 mg of pepper extract;
between about 100 mg to about 300 mg of dicalcium phosphate;
between about 25 mg to about 75 mg of microcrystalline cellulose;
between about 10 mg to about 30 mg of stearic acid;
between about 10 mg to about 30 mg of croscarmellose sodium;
between about 5 mg to about 15 mg of magnesium trisillicate;
between about 5 mg to about 15 mg of magnesium stearate; and
between about 5 mg to about 15 mg of hydroxypropyl methylcellulose;
wherein the single-dosage formulation is administered in a form selected from a group consisting of a pill, a tablet, a caplet, a capsule, a chewable tablet, a quick dissolve tablet, an effervescent tablet, a hard gelatin capsule, a soft gelatin capsule, a liquid suspension or a food product.
20. The pharmaceutically-acceptable single-dosage formulation of claim 19 , wherein the formulation consists of:
about 300 mg of ascorbic acid
about 1200 IUs of cholecalciferol;
about 125 IUs of d-alpha tocopherol succinate;
about 35 mg of thiamine mononitrate;
about 5.1 mg of riboflavin;
about 50 mg of niacinamide;
about 50 mg of pyridoxine hcl;
about 2.5 mg of folic acid;
about 105 mcg of cyanocobalamin;
about 7.5 mg of d-calcium pantothenate;
about 450 mcg of d-biotin;
about 75 mg of dicalcium malate;
about 55 mg of dimagnesium malate;
about 55 mg of zinc bisglycinate chelate;
about 1.5 mg of copper amino acid chelate;
about 175 mcg of selenium amino acid chelate;
about 225 mcg of chromium amino acid chelate;
about 40 mg of alpha lipoic acid;
about 50 mg of co-enzyme Q-10;
about 3 mg of lutein;
about 750 mcg of lycopene;
about 7.5 mg of pepper extract;
about 200 mg of dicalcium phosphate;
about 50 mg of microcrystalline cellulose;
about 20 mg of stearic acid;
about 20 mg of croscarmellose sodium;
about 10 mg of magnesium trisillicate;
about 10 mg of magnesium stearate; and
about 10 mg of hydroxypropyl methylcellulose.