IP Library Granted Patent US 8,362,080
Granted Patent B2
US 8,362,080 · App. 12/641,894 · Granted Jan 29, 2013

Increasing glutathione levels for therapy

Inventor: Rajagopal V. Sekhar (Missouri City, TX)
Assignee: Baylor College of Medicine
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Quick Facts
Patent No.
US 8,362,080
App. No.
12/641,894
Granted
Jan 29, 2013
Kind
B2
Abstract

The present invention concerns compositions and methods related to utilizing glycine and N-acetylcysteine for a variety of methods, including, for example, reducing deleterious effects of oxidative stress; treating and/or preventing diabetes; and/or increasing GSH levels.

Claims (15)

1. A method of treating an individual for one or more medical conditions, comprising the step of providing an effective amount of a composition comprising glycine and n-acetylcysteine to the individual, wherein the medical condition is selected from:

(a) dyslipidemia and/or insulin resistance;

(b) obesity;

(c) fatty acid oxidation;

(d) diabetic dyslipidemia;

(e) elevated fatty acid levels;

(f) diabetic microvascular complication comprising nephropathy, retinopathy, and/or neuropathy;

(g) elevated cholesterol and/or triglyceride levels;

(h) fatty liver disease;

(i) neurodegenerative disease in aging;

(j) statin-induced myopathy; and/or

(k) HIV infection.

2. The method of claim 1 , wherein the glycine and n-acetylcysteine are provided to the individual in the same composition.

3. The method of claim 1 , wherein the glycine and n-acetylcysteine are provided to the individual in different compositions.

4. The method of claim 1 , wherein the glycine and n-acetylcysteine are provided orally to the individual.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2012
From: SEKHAR, RAJAGOPAL V.
To: BAYLOR COLLEGE OF MEDICINE
Reel/Frame 028789/0546 →
Continuity (2)
Provisional Application 61138591 · Dec 18, 2008
Related Publication 20110077303A1 · Mar 31, 2011