IP Library Granted Patent US 8,377,487
Granted Patent B2
US 8,377,487 · App. 12/812,208 · Granted Feb 19, 2013

Mixture of citric flavonoids to improve ruminal fermentation

Inventors: Maria del Mar Serra (Barcelona, ES); Fernando Heredia (Barcelona, ES); Francisco Javier Crespo (Barcelona, ES); Joaquim Balcells (Barcelona, ES)
Assignee: Exquim, S.A.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,377,487
App. No.
12/812,208
Granted
Feb 19, 2013
Kind
B2
Abstract

The invention refers to the use of a mixture of naringin, bitter orange extract and sepiolite to improve ruminal fermentation in ruminants.

Claims (14)

1. A method for limiting the growth of bacteria causing ruminal acidosis which comprises feeding a mixture comprising 10% to 25% by weight of naringin, 10% to 65% by weight of bitter orange extract and sufficient quantity up to 100% by weight of sepiolite, to a ruminant with ruminal acidosis so as to improve ruminal fermentation in the ruminant, wherein the bitter orange extract comprises neohesperidine and poncirin, and wherein said improvement comprises limiting the growth of bacteria causing ruminal acidosis.

2. The method of claim 1 , wherein the mixture comprises 15% to 25% by weight of naringin, 20% to 60% by weight of bitter orange extract and sufficient quantity up to 100% of sepiolite.

3. The method of claim 2 , wherein the mixture comprises 20% by weight of naringin, 40% by weight of bitter orange extract and 40% by weight of sepiolite.

4. The method of any one of claims 1 to 3 , wherein the bitter orange extract comprises 31.5 to 71.5% of flavonoids with respect to the total weight percent of the bitter orange extract.

5. The method of any one of claims 1 to 3 , wherein the bitter orange extract comprises 44 to 55% of flavonoids with respect to the total weight percent of the bitter orange extract.

6. The method of claim 4 , wherein the flavonoids within the bitter orange extract comprise (a) 17.5 to 35.1% by weight of naringin, (b) 7.7 to 16.9% by weight of neohesperidine and (c) 2.1 to 6.5% by weight of poncirin and wherein the weight percentages are in reference to the total weight of the flavonoids within the bitter orange extract.

7. The method of claim 4 , wherein the flavonoids within the bitter orange extract comprise (a) 25 to 27% by weight of naringin, (b) 11 to 13% by weight of neohesperidine and (c) 3 to 5% by weight of poncirin and wherein the weight percentages are in reference to the total weight of the flavonoids within the bitter orange extract.

8. The method of claim 1 , wherein said improvement regulates the microbial fermentation processes in the ruminant that is administered concentrated food rations.

9. The method of claim 1 , wherein the bacteria causing ruminal acidosis is Streptococcus bovis .

10. The method of claim 1 , wherein said improvement optimises production in the intensive fattening of ruminants.

11. The method of claim 10 , wherein the ruminants are calves.

12. The method of claim 1 , which comprises adding the mixture to feed in solid form at concentrations of 10 to 2000 ppm in weight.

13. The method of claim 1 , which comprises adding the mixture to feed in solid form at concentrations of 50 to 1000 ppm in weight.

14. The method of claim 1 , which comprises adding the mixture to feed in solid form at concentrations of 100 to 300 ppm in weight.

Assignments (3)
MERGER Recorded Aug 12, 2020
From: EXQUIM, S.A.
To: INTERQUIM, S.A.
Reel/Frame 053465/0902 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2020
From: INTERQUIM, S.A.
To: HEALTHTECH BIO ACTIVES, S.L.U.
Reel/Frame 053466/0233 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2010
From: DEL MAR SERRA, MARIA; HEREDIA, FERNANDO; CRESPO, FRANCISCO JAVIER; BALCELLS, JOAQUIM
To: EXQUIM, S.A.
Reel/Frame 024713/0268 →
Priority Claims (1)
EP 08150133 · Jan 9, 2008 · regional
Continuity (1)
Related Publication 20100291239A1 · Nov 18, 2010