IP Library Granted Patent US 8,398,628
Granted Patent B2
US 8,398,628 · App. 12/562,625 · Granted Mar 19, 2013

Eye therapy system

Inventor: David Muller (Boston, MA)
Assignee: Avedro, Inc.
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Quick Facts
Patent No.
US 8,398,628
App. No.
12/562,625
Granted
Mar 19, 2013
Kind
B2
Abstract

The cornea is reshaped in multiple steps according to varying amounts of energy in varying patterns and/or at varying locations to achieve a customized reshaping of the cornea to address the specific needs of an individual patient. The varying amounts of energy may be applied via one or more conducting elements, which include an outer conductor and an inner conductor disposed within the outer conductor, a distal end of the outer conductor and the inner conductor defining the varying patterns. For example, one step may form a substantially circular lesion to flatten a first portion of the cornea to treat presbyopia, while another step may form a substantially circular and concentric lesion having a greater diameter to steepen a second portion of the cornea to treat hyperopia. Advantageously, continuous transitional regions are formed relative to the reshaped portions to provide vision for intermediate distances.

Claims (19)

1. A system for applying therapy to an eye, the system comprising:

at least one energy conducting element configured to apply an initial amount of energy according to an initial pattern to an eye, the initial amount of energy according to the initial pattern causing a reshaping of an aspect of the eye, the at least one energy conducting element including an inner conductor and an outer conductor separated by a gap, a distal end of the outer conductor and the inner conductor defining the initial pattern;

a measurement device operable to measure an amount of reshaping in response to an application of the initial amount of energy according to the initial pattern and provide a feedback indication of the measured amount of reshaping; and

a controller operably coupled to the at least one energy conducting element and the measurement device, the controller being configured to:

receive the feedback indication of the amount of reshaping from the measurement device and, in response, to the feedback indication of the amount of reshaping,

determine a second amount of energy and a different pattern based on the feedback indication of the reshaping received from the measurement device, the at least one energy conducting element being configured to apply the second amount of energy according to the different pattern to the eye, and

cause the at least one energy conducting element to apply the second amount of energy according to the different pattern to the eye, the second amount of energy according to the different pattern causing a different reshaping of the aspect of the eye.

2. The system according to claim 1 , further comprising a plurality of replaceable end pieces, the distal end of the outer conductor and the inner conductor being defined by at least one of the plurality of replaceable end pieces.

3. The system according to claim 2 , wherein each of the plurality of replaceable end pieces has a different shape.

4. The system according to claim 2 , wherein each of the plurality of replaceable end pieces has different dimensions.

5. The system according to claim 2 , wherein a first one of the plurality of replaceable end pieces is attached to the at least one energy conducting element to apply the initial amount of energy according to the initial pattern, and a second one of the plurality of replaceable end pieces is attached to the at least one energy conducting element to apply the second amount of energy according to the different pattern.

6. The system according to claim 1 , wherein the at least one energy conducting element includes a first energy conducting element and a second energy conducting element, the distal end of the first energy conducting element defines the initial pattern, and the distal end of the second energy conducting element defines the different pattern.

7. The system according to claim 1 , further comprising a sheet of dielectric material covering the distal end to provide a bottom surface of a substantially enclosed assembly that includes the at least one energy conducting element.

8. The system according to claim 7 , further comprising:

a coolant supply; and

a coolant delivery system in communication with the coolant supply, the substantially enclosed assembly further including the coolant delivery system, the controller being further configured to cause the coolant delivery system to deliver a pulse of coolant to the dielectric material.

9. The system according to claim 1 , wherein the measurement device includes keratometer.

10. The system according to claim 1 , wherein the initial amount of energy according to the initial pattern is applied at a first location relative to the eye and the second amount of energy according to the different pattern is applied at a second location relative to the eye, the first location being different than the second location, the controller being configured to determine the second location based on the feedback indication of reshaping received from the measurement device.

11. The system according to claim 1 , wherein the controller is further configured to compare the feedback indication of reshaping to a threshold amount of reshaping and determine whether to apply the second amount of energy according to the different pattern based on the comparison.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Nov 21, 2019
From: ORBIMED ROYALTY OPPORTUNITIES II, LP
To: AVEDRO, INC.
Reel/Frame 051080/0756 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT SERIAL NO. 14/140,184 PREVIOUSLY RECORDED AT REEL: 042167 FRAME: 0671. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded May 1, 2017
From: AVEDRO, INC.
To: ORBIMED ROYALTY OPPORTUNITIES II, LP
Reel/Frame 042390/0659 →
SECURITY INTEREST Recorded Apr 27, 2017
From: AVEDRO, INC.
To: ORBIMED ROYALTY OPPORTUNITIES II, LP
Reel/Frame 042167/0671 →
SECURITY AGREEMENT Recorded Feb 13, 2012
From: AVEDRO, INC.
To: VENTURE LENDING & LEASING VI, INC.
Reel/Frame 027697/0305 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2009
From: MULLER, DAVID
To: AVEDRO, INC.
Reel/Frame 023261/0962 →
Continuity (3)
Provisional Application 61098489 · Sep 19, 2008
Provisional Application 61101503 · Sep 30, 2008
Related Publication 20100076423A1 · Mar 25, 2010