Multi-piece antimicrobial dressing and percutaneous device securement cover
The present invention is related to a polymeric delivery vehicle for delivery of bioactive agents, and preferably, for the delivery of one or more bioactive agents. The device, when applied as described herein, provides substantially complete anti-microbial coverage around the entry point of a percutaneous device and, preferably for a length greater than the diameter of the device.
1. A percutaneous device dressing for use with a percutaneous medical device that has punctured the skin of a patient and which has a portion of the percutaneous medical device protruding from the skin, comprising:
a) a top and a bottom dressing, both being formed from a flexible material and having upper and lower surfaces, with the lower surface being skin facing in use, b) an overdressing layer and c) a bioactive agent that is incorporated into the top and bottom dressings and/or onto the lower surfaces of the top and bottom dressings;
wherein the top dressing is secured to the overdressing layer and has a shape that surrounds at least a portion of the percutaneous medical device protruding from the skin and the bottom dressing that is separate from the top dressing and the overdressing layer prior to application and has a shape that substantially completes a perimeter proximate to the percutaneous medical device,
wherein when the top dressing and the bottom dressing are placed in a side-by-side position to surround the percutaneous medical device, the perimeter formed by adjacent positioning of the top dressing and the bottom dressing substantially conforms to size and shape of the percutaneous medical device.
2. A device according to claim 1 wherein the top dressing and bottom dressing comprise gelatin, collagen, and polysaccharides.
3. A device according to claim 2 wherein the bioactive agent is an antimicrobial agent.
4. A device according to claim 3 wherein said antimicrobial agent comprises chlorhexidine.
5. A device according to claim 1 , wherein the top and bottom dressings are formed into a unitary dressing and are joined together on the patient's skin surface.
6. A dressing according claim 1 , wherein the overdressing layer is an occlusive or semi-occlusive layer.
7. A dressing according to claim 6 , wherein the overdressing layer is as an adhesive film.
8. A method of dressing the puncture site of a percutaneous medical device for a patient using a percutaneous device dressing having
a top and a bottom dressing, both being formed from a flexible material and having upper and lower surfaces, with the lower surface being skin facing in use; an overdressing layer and a bioactive agent that is incorporated into the top and bottom dressings and/or onto the lower surfaces of the top and bottom dressings, wherein the top dressing is secured to the overdressing layer and has a shape that surrounds at least a portion of the percutaneous medical device protruding from the skin and the bottom dressing is separate from the top dressing and the overdressing layer and has a shape that substantially completes a perimeter proximate to the percutaneous medical device;
wherein when the top dressing and the bottom dressing are placed in a side-by-side position to surround the percutaneous medical device, the perimeter formed by adjacent positioning of the top dressing and the bottom dressing substantially conforms to size and shape of the percutaneous medical device;
comprising:
a) sliding the bottom dressing in place next to the skin of the patient to allow the bottom dressing to surround a portion of a perimeter proximate to the percutaneous medical device at the puncture site such that the lower surface of the bottom dressing is in contact with the skin surrounding the puncture site while the upper surface of the bottom dressing is in contact with a portion of the medical device protruding from the skin;
b) applying the top dressing in conjunction with the bottom dressing such that its lower surface is in contact with a portion of the skin along at least a portion of the perimeter proximate to the percutaneous medical device;
and
c) fixing the top and bottom dressings and percutaneous medical device to the skin with the overdressing layer.
9. A method according to claim 8 wherein the top dressing and bottom dressing comprise gelatin, collagen, and polysaccharides.
10. A method according to claim 8 wherein the bioactive agent is an antimicrobial agent.
11. A method according to claim 10 wherein said antimicrobial agent comprises chlorhexidine.
12. A method according to claim 8 , wherein the top and bottom dressings are formed into a unitary dressing and are joined together on the patient's skin surface.
13. A method according claim 8 , wherein the overdressing layer is an occlusive or semi-occlusive layer.
14. A dressing according to claim 13 , wherein the overdressing layer is as an adhesive film.