IP Library Granted Patent US 8,587,307
Granted Patent B2
US 8,587,307 · App. 12/833,355 · Granted Nov 19, 2013

Systems and methods for accelerating the acquisition and reconstruction of magnetic resonance images with randomly undersampled and uniformly undersampled data

Inventors: Lei Ying (Milwaukee, WI); Dong Liang (Milwaukee, WI)
Assignee: UWM Research Foundation, Inc.
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Quick Facts
Patent No.
US 8,587,307
App. No.
12/833,355
Granted
Nov 19, 2013
Kind
B2
Abstract

A method and system of accelerating the acquisition and reconstruction of magnetic resonance images. Magnetic resonance imaging (“MRI”) data is acquired from a plurality of coils using parallel MRI (“pMRI”). The MRI data represents a reduced field-of-view (“FOV”) image for each of a plurality of coils. The MRI data is further undersampled by sequentially applying a compressed sensing (“CS”) technique, such as SparseMRI. The undersampled, reduced FOV images are then reconstructed into a final magnetic resonance image using a pMRI reconstruction technique, such as SENSitivity encoding (“SENSE”). This combination of MR image acquisition, sampling, and reconstruction is referred to as CS-SENSE.

Claims (42)

1. A method of reconstructing magnetic resonance (“MR”) images, the method comprising:

obtaining a first set of data from a first receiver coil associated with an MR imaging device, the first set of data being a randomly undersampled subset of uniformly undersampled data;

generating a second set of data based on the first set of data, the second set of data being a set of uniformly undersampled data and being associated with a first reduced field-of-view (“FOV”) image;

obtaining a third set of data from a second receiver coil associated with an MR imaging device, the third set of data also being a randomly undersampled subset of uniformly undersampled data;

generating a fourth set of data based on the third set of data, the fourth set of data also being a set of uniformly undersampled data and being associated with a second reduced FOV image;

generating a fifth set of data based on the second set of data and the fourth set, the fifth set of data being associated with a reconstructed full FOV image; and

generating, using a processor associated with the MR imaging device, the reconstructed full FOV image based on the fifth set of data.

2. The method of claim 1 , further comprising applying a sensitivity modulation to the first receiver coil and the second receiver coil.

3. The method of claim 1 , further comprising

applying a convex optimization to the first set of data in order to generate the second set of data, and

applying a convex optimization to the third set of data in order to generate the fourth set of data.

4. The method of claim 1 , further comprising applying a selected sampling pattern in order to obtain the first set of data.

5. The method of claim 4 , wherein the sampling pattern is a random sampling pattern based on a compressed sensing.

6. A system configured for reconstructing magnetic resonance (“MR”) images, the system comprising:

a processing unit associated with an MR imaging device, the processing unit configured to

obtain a first set of data from a first receiver coil associated with an MR imaging device, the first set of data being a randomly undersampled subset of uniformly undersampled data,

generate a second set of data based on the first set of data, the second set of data being a set of uniformly undersampled data and being associated with a first reduced field-of-view (“FOV”) image,

obtain a third set of data from a second receiver coil associated with an MR imaging device, the third set of data also being a randomly undersampled subset of uniformly undersampled data,

generate a fourth set of data based on the third set of data, the fourth set of data also being a set of uniformly undersampled data and being associated with a second reduced FOV image,

generate a fifth set of data based on the second set of data and the fourth set of data, the fifth set of data being associated with a reconstructed full FOV image, and

generate the reconstructed full FOV image based on the fifth set of data.

7. The system of claim 6 , wherein the processing unit is further configured in order to apply a sensitivity modulation to the first receiver coil and the second receiver coil.

8. The system of claim 6 , wherein the processing unit is further configured in order to

apply a convex optimization to the first set of data in order to generate the second set of data, and

apply a convex optimization to the third set of data in order to generate the fourth set of data.

9. The system of claim 6 , wherein the processing unit is further configured in order to apply a selected sampling pattern in order to obtain the first set of data.

10. The system of claim 9 , wherein the sampling pattern is a random sampling pattern based on a compressed sensing.

11. A method of magnetic resonance (“MR”) image reconstruction configured for use with an MR imaging device, the method comprising:

(a) randomly undersampling uniformly undersampled signals from each of a plurality of receiver coils based on compressed sensing in order to generate a first set of data;

(b) applying a convex optimization to the first set of data in order to generate a second set of data, the second set of data being associated with a uniformly undersampled reduced field-of-view (“FOV”) image from each of the plurality of receiver coils;

(c) applying a parallel magnetic resonance imaging (“pMRI”) reconstruction to the second set of data in order to generate a third set of data, the third set of data being associated with a reconstructed full FOV image; and

(d) generating, using a processor associated with the MR imaging device, the reconstructed full FOV image based on the third set of data.

12. The method of claim 11 , wherein the plurality of receiver coils includes eight receiver coils.

13. The method of claim 11 , wherein an overall data reduction factor associated with the reconstructed full FOV image is a product of a first reduction factor resulting from sampling signals from each of the plurality of receiver coils based on a compressed sensing and a second reduction factor resulting from applying the pMRI reconstruction.

14. A system configured for reconstructing magnetic resonance (“MR”) images, the system comprising:

a processing unit associated with an MR imaging device, the processing unit configured to

(a) randomly undersample uniformly undersampled signals from each of a plurality of receiver coils based on compressed sensing in order to generate a first set of data,

(b) apply a convex optimization to the first set of data in order to generate a second set of data, the second set of data being associated with a uniformly undersampled, reduced field-of-view (“FOV”) image from each of the plurality of receiver coils,

(c) apply a parallel magnetic resonance imaging (“pMRI”) reconstruction to the second set of data in order to generate a third set of data, the third set of data being associated with a reconstructed full FOV image, and

(d) generate the reconstructed full FOV image based on the third set of data.

15. The system of claim 14 , wherein the plurality of receiver coils includes eight receiver coils.

16. The system of claim 14 , wherein an overall data reduction factor associated with the reconstructed full FOV image is a product of a first reduction factor resulting from sampling signals from each of the plurality of receiver coils based on a compressed sensing and a second reduction factor resulting from applying the pMRI reconstruction.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 2, 2015
From: UNIVERSITY OF WISCONSIN MILWAUKEE
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 034719/0413 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 19, 2010
From: YING, LEI; LIANG, DONG
To: UWM RESEARCH FOUNDATION, INC.
Reel/Frame 024707/0375 →
Continuity (2)
Provisional Application 61224350 · Jul 9, 2009
Related Publication 20110006768A1 · Jan 13, 2011