IP Library › Granted Patent US 8,597,289
Granted Patent B2
US 8,597,289 · App. 12/696,930 · Granted Dec 3, 2013

Cervical opening sealing devices

Inventors: Russell K. Layton, Jr. (Acton, MA); Lionel Stewart MacLean (Allston, MA); David Freed (Westborough, MA); Brian Hanley (Framingham, MA)
Assignee: Cytyc Corporation
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Quick Facts
Patent No.
US 8,597,289
App. No.
12/696,930
Granted
Dec 3, 2013
Kind
B2
Abstract

A device for sealing a cervical opening includes a support structure, and a seal coupled to the support structure, the seal having a surface for abutting against tissue next to the cervical opening, wherein the seal is tiltable relative to the support structure. A device for sealing a cervical opening includes a support structure, and a member coupled to the support structure, wherein the member is inflatable to create a seal for abutting against cervical tissue. A device for sealing a cervical opening includes a seal having a surface for contacting tissue next to the cervical opening, an opening formed on the surface of the seal, and a vacuum port, wherein the opening is in fluid communication with the vacuum port.

Claims (17)

1. A device for sealing a cervical opening of a uterus, comprising:

an elongate support structure having a proximal end and a distal end, and defining an axial lumen therethrough in communication with an opening in the distal end;

a sealing member, the sealing member having a distal surface configured for contacting tissue surrounding the cervical opening, and a proximal surface configured to receive the distal end of the elongate support structure, wherein the distal end of the elongate support structure is configured to seat within and thereby form a seal with the proximal surface of the sealing member, and wherein the sealing member may be tilted relative to the distal end of the support structure to maintain a seal when the elongate support structure is not orthogonal with the tissue surrounding the cervical opening, the sealing member having a central opening therein so that the axial lumen of the support structure is in communication with an interior region of the uterus via the open end of the elongate support structure when a seal is formed by the elongate support structure and sealing member; and

an ablation device disposed within the axial lumen of the elongate support structure and the central opening of the sealing member, the ablation device comprising an expandable distal portion configured to expand when the distal portion of the ablation device is disposed within the uterus.

2. The device of claim 1 , wherein the distal end of the elongate support structure has a rounded configuration, and wherein the sealing member is rotatably coupled to the distal end of the elongate support structure while a seal is formed by the elongate support structure and sealing member.

3. The device of claim 1 , wherein the distal end of the elongate support structure comprises a convex surface, and the proximal surface of the sealing member comprises a concave surface.

4. The device of claim 1 , further comprising a tubular member disposed within the axial lumen of the elongate support structure, the tubular member configured to allow passage of devices, agents or fluid into the uterus.

5. A device for sealing a cervical opening of a uterus, comprising:

an elongate support structure having a proximal end and a distal end, and defining an axial lumen therethrough; and

a tapered sealing member rotatably carried on the distal end of the support structure, the tapered sealing member comprising an outer surface and an inner surface, the inner surface defining a central axial lumen through which the elongate support structure extends, the outer surface configured for contacting tissue surrounding the cervical opening and comprising one or more openings therein, wherein each of the one or more openings is in fluid communication with a vacuum port, such that a vacuum source placed in fluid communication with the vacuum port would cause cervical wall tissue to be drawn against, and thereby form a seal with, the outer surface of the sealing member,

wherein the elongate support structure may be rotated relative to the sealing member, while a seal is maintained between the outer surface of the sealing member and cervical wall tissue.

6. The device of claim 5 , wherein the one or more openings comprise a plurality of openings distributed circumferentially about the outer surface of the sealing member.

7. The device of claim 5 , wherein the one or more openings are in fluid communication with a common channel, and the common channel is in fluid communication with the vacuum port.

8. The device of claim 7 , wherein the common channel comprises a ring configuration disposed within the sealing member.

9. The device of claim 5 , further comprising a pressure sensing device coupled to the sealing member.

10. The device of claim 5 , further comprising a tubular member disposed within the axial lumen of the elongate support structure, the tubular member configured to allow passage of devices, agents or fluid into an interior region of the uterus.

11. The device of claim 5 , further comprising an ablation device disposed within the axial lumen of the elongate support structure, the ablation device comprising an expandable distal portion configured to expand when the distal portion of the ablation device is disposed within the uterus.

Assignments (11)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: CITIBANK, N.A., AS COLLATERAL AGENT
Reel/Frame 075926/0339 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
TERMINATION OF PATENT SECURITY AGREEMENTS AND RELEASE OF SECURITY INTERESTS Recorded Aug 26, 2010
From: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
To: HOLOGIC, INC.; R2 TECHNOLOGY, INC.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; DIRECT RADIOGRAPHY CORP.; CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS III, INC.; CYTYC PRENATAL PRODUCTS CORP.; THIRD WAVE TECHNOLOGIES, INC.
Reel/Frame 024892/0001 →
NINETEENTH SUPPLEMENT TO PATENT SECURITY AGREEMENT Recorded Feb 18, 2010
From: CYTYC CORPORATION
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 023958/0039 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2010
From: LAYTON, RUSSELL K.; MACLEAN, LIONEL STEWART; FREED, DAVID; HANLEY, BRIAN
To: CYTYC CORPORATION
Reel/Frame 023874/0342 →
Continuity (2)
Provisional Application 61148725 · Jan 30, 2009
Related Publication 20100198214A1 · Aug 5, 2010