Analgesic agents
The invention provides a compound of formula (I) or a salt thereof, as well as compositions comprising such compounds. The compounds and compositions are useful as analgesics.
1. A compound of formula (I):
or a salt thereof.
2. The compound of claim 1 which is a compound of formula (I) or a pharmaceutically acceptable salt thereof.
3. A pharmaceutical composition comprising a compound of formula (I) as described in claim 1 , or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable diluent or carrier.
4. A method for producing analgesia in an animal comprising administering a compound of formula (I) as described in claim 1 , or a pharmaceutically acceptable salt thereof, to the animal.
5. A method for producing analgesia in an animal, comprising administering to the animal an amount of a compound of formula (I) as described in claim 1 , or a pharmaceutically acceptable salt thereof, that is effective to produce analgesia while causing less inhibition of GI transit than is caused by administration of a similar effective dosage of morphine to the animal.
6. A method for producing analgesia in an animal, comprising administering to the animal an amount of a compound of formula (I) as described in claim 1 , or a pharmaceutically acceptable salt thereof, that is effective to produce analgesia while causing less dependence than is caused by administration of a similar effective dosage of morphine to the animal.
7. A method for producing analgesia in an animal, comprising administering to the animal an amount of a compound of formula (I) as described in claim 1 , or a pharmaceutically acceptable salt thereof, that is effective to produce analgesia while causing less tolerance than is caused by administration of a similar effective dosage of morphine to the animal.
8. The method of claim 4 , wherein the animal is a human.