IP Library Granted Patent US 8,616,702
Granted Patent B2
US 8,616,702 · App. 13/203,168 · Granted Dec 31, 2013

Hybrid laser ophthalmoscope

Inventor: Michael Abrámoff (Iowa City, IA)
Assignee: University of Iowa Research Foundation
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Quick Facts
Patent No.
US 8,616,702
App. No.
13/203,168
Granted
Dec 31, 2013
Kind
B2
Abstract

Provided is a hybrid laser ophthalmoscope comprising a laser light source, a LED light source, and a holographic diffuser, wherein the holographic diffuser is configured to shape a beam of light into a Maxwellian ring.

Claims (48)

1. An apparatus for examining an eye, comprising:

a first light source, wherein the first light source is a laser light source;

a second light source, wherein the second light source is a Light Emitting Diode (LED) light source;

a light source selection switch, coupled to the first light source and the second light source, configured to select either the first light source or the second light source to illuminate an eye, wherein the first light source or the second light source becomes a selected light source upon selection;

a holographic diffuser configured to receive light from the selected light source and to shape the light into a Maxwellian ring based on a diffraction pattern of the holographic diffuser; and

an imaging lens coupled with a hole mirror, wherein the imaging lens and the hole mirror are configured to receive the Maxwellian ring and to image the Maxwellian ring onto the eye.

2. The apparatus of claim 1 , wherein the first light source transmits laser light at 785 nm.

3. The apparatus of claim 1 , wherein the second light source transmits red, green, or white light.

4. The apparatus of claim 1 , wherein the first light source is selected for imaging blood flow and/or blood vessels having blood flow in the eye.

5. The apparatus of claim 1 , wherein the second light source is selected for imaging exudates and other lesions not primarily consisting of blood, that can occur in diabetic retinopathy, hypertension, or macular degeneration.

6. The apparatus of claim 1 , wherein the holographic diffuser is generated as a digital hologram, based on a Fourier transform expanded in a Bessel function basis.

7. The apparatus of claim 1 , wherein the holographic diffuser is configured to be swappable with a second holographic diffuser in order to adjust a ring diameter and local propagation direction of the light at a pupil of the eye on a per-patient basis.

8. The apparatus of claim 1 , further comprising:

a sensor, configured to receive light reflected from the imaging of the Maxwellian ring and generate an image of the eye based on the reflected light.

9. The apparatus of claim 8 , wherein the sensor is a complementary metal oxide semiconductor (CMOS) area sensor.

10. The apparatus of claim 1 , further comprising a dichroic mirror that is used to direct light from the first light source or the second light source into the eye.

11. The apparatus of claim 1 , further comprising a beamsplitter that is used to direct light from the first light source or the second light source into the eye.

12. A method for examining an eye, comprising:

selecting from a first light source and a second light source, wherein the first light source is a laser light source and the second light source is a Light Emitting Diode (LED) light source, resulting in a selected light source;

transmitting light from the selected light source to a holographic diffuser, wherein the holographic diffuser is configured to shape the light into a Maxwellian ring based on a diffraction pattern of the holographic diffuser;

transmitting the Maxwellian ring from the holographic diffuser to an imaging lens coupled with a hole mirror, wherein the imaging lens and the hole mirror are configured to image the Maxwellian ring based on the diffraction pattern of the holographic diffuser onto the eye; and

imaging the eye with the Maxwellian ring.

13. The method of claim 12 , wherein the first light source transmits laser light at 785 nm.

14. The method of claim 12 , wherein the second light source transmits red, green, or white light.

15. The method of claim 12 , wherein the first light source is selected for imaging blood flow and/or blood vessels having blood flow in the eye.

16. The method of claim 12 , wherein the second light source is selected for imaging exudates and other lesions not primarily consisting of blood, that can occur in diabetic retinopathy, hypertension, or macular degeneration.

17. The method of claim 12 , further comprising:

generating the holographic diffuser as a digital hologram, based on a Fourier transform expanded in a Bessel function basis.

18. The method of claim 12 , further comprising:

swapping the holographic diffuser with a second holographic diffuser in order to adjust a ring diameter and local propagation direction of the light at a pupil of the eye on a per-patient basis.

19. The method of claim 12 , further comprising:

receiving light reflected from illuminating the eye with the Maxwellian ring; and

generating an image of the eye based on the reflected light.

20. The method of claim 19 , wherein a complementary metal oxide semiconductor (CMOS) area sensor receives the light reflected and generates the image.

21. The method of claim 12 , wherein transmitting light from the selected light source to a holographic diffuser comprises transmitting the selected light source through a dichroic mirror that is used to direct light from the selected light source into the eye.

22. The method of claim 12 , wherein transmitting light from the selected light source to a holographic diffuser comprises transmitting the selected light source through a beamsplitter that is used to direct light from the selected light source into the eye.

23. A system for examining an eye, comprising:

an apparatus comprising,

a first light source, wherein the first light source is a laser light source,

a second light source, wherein the second light source is a Light Emitting Diode (LED) light source,

a light source selection switch, coupled to the first light source and the second light source, configured to select either the first light source or the second light source to illuminate an eye, wherein the first light source or the second light source becomes a selected light source upon selection,

a holographic diffuser configured to receive light from the selected light source and to shape the light into a Maxwellian ring based on a diffraction pattern of the holographic diffuser,

an imaging lens coupled with a hole mirror, wherein the imaging lens and the hole mirror are configured to receive the Maxwellian ring and to image the Maxwellian ring onto the eye, and

a sensor, configured to receive light reflected from the imaging of the Maxwellian ring and generate an image of the eye based on the reflected light; and

a computing device, coupled to the apparatus, configured to analyze the image of the eye.

24. The system of claim 23 , wherein the computing device is configured to analyze the image of the eye to identify blood flow, blood vessels having blood flow, and/or exudates and other lesions not primarily consisting of blood, that can occur in diabetic retinopathy, hypertension, or macular degeneration.

25. The system of claim 23 , wherein the apparatus further comprises a dichroic mirror that is used to direct light from the first light source or the second light source into the eye.

26. The system of claim 23 , wherein the apparatus further comprises a beamsplitter that is used to direct light from the first light source or the second light source into the eye.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 16, 2014
From: UNIVERSITY OF IOWA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 032040/0596 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2011
From: ABRAMOFF, MICHAEL
To: UNIVERSITY OF IOWA RESEARCH FOUNDATION
Reel/Frame 027234/0737 →
Continuity (2)
Provisional Application 61155425 · Feb 25, 2009
Related Publication 20120069299A1 · Mar 22, 2012