IP Library › Granted Patent US 8,628,965
Granted Patent B2
US 8,628,965 · App. 13/400,173 · Granted Jan 14, 2014

Composition of cultured grape cells

Inventors: Yuval Eshdat (Rechovot, IL); Avi Perl (Rishon-lezion, IL)
Assignee: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O), The Volcani Center
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Quick Facts
Patent No.
US 8,628,965
App. No.
13/400,173
Granted
Jan 14, 2014
Kind
B2
Abstract

A pharmaceutical or nutraceutical composition comprising a cell line callus culture of grape berry cells grown in vitro, whereby the cell line callus culture of grape berry cells is derived from one or more of grape-berry cross section, grape-berry skin, grape-berry flesh, grape seed, grape embryo of seeded or seedless cultivars or grape seed coat.

Claims (27)

1. A composition consisting essentially of:

a non-extracted, dry cell line callus culture of grape berry cells grown in vitro, whereby the cell line callus culture of grape berry cells is derived from one or more of grape-berry cross section, grape-berry skin, grape-berry flesh, grape seed, grape embryo of seeded or seedless cultivars or grape seed coat;

wherein the composition is a nutraceutical composition.

2. The composition of claim 1 , wherein the composition further comprises a nutraceutical acceptable carrier.

3. The composition of claim 1 , wherein said cell line callus culture comprises at least 0.5% polyphenols.

4. The composition of claim 3 , wherein said cell line callus culture comprises at least 2% polyphenols.

5. The composition of claim 1 , wherein said cell line callus culture is derived from a colored or a non-colored grape.

6. The composition of claim 1 , wherein said composition is designed for a mucosal delivery.

7. The composition of claim 1 , wherein said composition is tasteless.

8. The composition of claim 1 , wherein said composition is in a form of mouthwash, a strip, a foam, a powder, a chewing gum, an oral spray, a lozenge, a capsule, a and toothpaste.

9. The composition of claim 1 , wherein said composition is in a form of a powder.

10. An alcohol free composition consisting essentially of:

a non-extracted, dry cell line callus culture of grape berry cells grown in vitro, whereby the cell line callus culture of grape berry cells is derived from one or more of grape-berry cross section, grape-berry skin, grape-berry flesh, grape seed, grape embryo of seeded or seedless cultivars or grape seed coat;

wherein the composition is a nutraceutical or a pharmaceutical composition and comprises less than 1% alcohol.

11. A low sugar composition consisting essentially of:

a non-extracted, dry cell line callus culture of grape berry cells grown in vitro, whereby the cell line callus culture of grape berry cells is derived from one or more of grape-berry cross section, grape-berry skin, grape-berry flesh, grape seed, grape embryo of seeded or seedless cultivars or grape seed coat; wherein the composition is a nutraceutical or a pharmaceutical composition and said cell line callus culture of grape berry cells comprises less than 10% sweetening sugar.

12. A composition consisting essentially of:

a non-extracted, dry cell line callus culture of grape berry cells grown in vitro, whereby the cell line callus culture of grape berry cells is derived from one or more of grape-berry cross section, grape-berry skin, grape-berry flesh, grape seed, grape embryo of seeded or seedless cultivars or grape seed coat;

wherein the composition is a pharmaceutical composition.

13. The composition of claim 12 , wherein said composition further comprises a pharmaceutically acceptable carrier.

14. The composition of claim 12 , wherein said cell line callus culture comprises at least 0.5% polyphenols.

15. The composition of claim 14 , wherein said cell line callus culture comprises at least 2% polyphenols.

16. The composition of claim 12 , wherein said cell line callus culture is derived from a colored or a non-colored grape.

17. The composition of claim 12 , wherein said composition is designed for a mucosal delivery.

18. The composition of claim 12 , wherein said composition is tasteless.

19. The composition of claim 12 , wherein said composition is in a form of a mouthwash, a strip, a foam, a chewing gum, an oral spray, a lozenge, a capsule, a toothpaste and a food.

20. The composition of claim 19 , wherein said composition is in a form of a powder.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 19, 2013
From: ESHDAT, YUVAL; PERL, AVI
To: THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O), THE VOLCANI CENTER
Reel/Frame 031625/0376 →
Continuity (3)
Division 11884774
Provisional Application 60655918 · Feb 25, 2005
Related Publication 20130064797A1 · Mar 14, 2013