Patent
The invention relates to a composition comprising an effective amount of at least one of the strains selected from the group consisting of Lactobacillus plantarum CECT 7527, Lactobacillus plantarum CECT 7528, and Lactobacillus plantarum CECT 7529, These new strains have good probiotic features and are useful for the prevention and/or the treatment of cardiovascular disorders.
1. A composition comprising an effective amount of at least one of the strains selected from the group consisting of Lactobacillus plantarum CECT 7527 , Lactobacillus plantarum CECT 7528 , Lactobacillus plantarum CECT 7529, and mutant strains thereof, wherein the mutant strains are obtained by using the deposited strains as starter material, and wherein the mutant strains retain or further improve the cholesterol lowering activity of the parent strains.
2. The composition according to claim 1 , which comprises an effective amount of the strains Lactobacillus plantarum CECT 7527 , Lactobacillus plantarum CECT 7528, and Lactobacillus plantarum CECT 7529.
3. A pharmaceutical and/or veterinary product comprising an effective amount of the composition of claim 1 , together with appropriate amounts of pharmaceutically or veterinary acceptable excipients.
4. An edible product comprising an effective amount of the composition of claim 1 , together with appropriate amounts of other edible ingredients.
5. The edible product according to claim 4 , which is a dietary supplement.
6. The edible product according to claim 5 , which is a nutraceutical.
7. The edible product according to claim 4 , which is in the form of a tablet, capsule, syrup or pill.
8. The edible product according to claim 4 , which is a dairy product or a meat product.
9. A strain of Lactobacillus plantarum selected from the group consisting of Lactobacillus plantarum CECT 7527 , Lactobacillus plantarum CECT 7528 and Lactobacillus plantarum CECT 7529.
10. The composition according to claim 1 , which comprises an effective amount of at least one of the strains selected from the group consisting of Lactobacillus plantarum CECT 7527 , Lactobacillus plantarum CECT 7528, and Lactobacillus plantarum CECT 7529.
11. A method for the prevention and/or treatment of cardiovascular disorders in an animal, including a human, comprising:
administering to said animal in need thereof the composition of claim 1 .
12. The method according to claim 11 , which comprises administering an effective amount of the composition in combination with statins.
13. The method according to claim 11 , wherein the animal, including human, is sterol hyperabsorbent.
14. A method for reducing cholesterol in an animal, including a human, comprising:
administering to said animal in need thereof the composition of claim 1 .
15. The method according to claim 14 , which comprises administering an effective amount of the composition in combination with statins.
16. The method according to claim 14 , wherein the animal, including human, is sterol hyperabsorbent.