Peptide and use thereof
The present invention provides a peptide comprising an amino acid sequence of SEQ ID NO: 1 and a pharmaceutically acceptable salt thereof effective for treating degenerative disc diseases, treating body organ fibrosis, treating cancer and/or treating glomerulosclerosis, and effective for the inhibition of TGF-beta 1 signaling.
1. A peptide consisting of an amino acid sequence of LQVVYLH (SEQ ID NO: 1), or pharmaceutically acceptable salt thereof.
2. A composition for treating degenerative disc disease, comprising the peptide of claim 1 or pharmaceutically acceptable salt thereof.
3. A composition for treating body organ fibrosis, cancer or glomerulosclerosis, comprising the peptide of claim 1 or pharmaceutically acceptable salt thereof.
4. The composition according to claim 3 , wherein the treatment of body organ fibrosis, cancer or glomerulosclerosis is by the inhibition of TGF-beta1 signaling.
5. A method for treating a degenerative disc disease, comprising administering to a subject the peptide of claim 1 or pharmaceutically acceptable salt thereof.
6. A method for treating body organ fibrosis, cancer or glomerulosclerosis, comprising administering to a subject the peptide of claim 1 or pharmaceutically acceptable salt thereof.